Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246442 | 1.00 | TRPV1 (0.56) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL27733182 | 1.00 | TRPV1 (0.56) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL8058501 | 1.00 | TRPV1 (0.56) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL8058497 | 1.00 | TRPV1 (0.56) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL8622204 | 0.99 | TRPV1 (0.58) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL3092862 | 0.99 | TRPV1 (0.58) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL9417659 | 0.89 | TRPV1 (0.50) | TRPV1ALDH1A1FNTAFNTBDHODH | |
| SCHEMBL9417658 | 0.89 | TRPV1 (0.50) | TRPV1ALDH1A1FNTAFNTBDHODH | |
| SCHEMBL15246439 | 0.88 | TRPV1 (0.52) | TRPV1ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL30218692 | 0.88 | TRPV1 (0.52) | TRPV1ALDH1A1ALOX15FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12146177-B2 | Methods of making and using E,Z,E-geranylgeranyl diphosphate | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2024-11-19 | — | — | US | claimed |
| US-12146177-B2 | Methods of making and using E,Z,E-geranylgeranyl diphosphate | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2024-11-19 | — | — | US | disclosed |
| US-20210285016-A1 | METHODS OF MAKING AND USING E,Z,E-GERANYLGERANYL DIPHOSPHATE | WISYS TECHNOLOGY FOUNDATION, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210285016-A1 | METHODS OF MAKING AND USING E,Z,E-GERANYLGERANYL DIPHOSPHATE | GGPS1, COASY, FDPS | TRPV1 4825/4885ALDH1A1 2411/4885ALOX15 452/4885 |
| US-12146177-B2 | Methods of making and using E,Z,E-geranylgeranyl diphosphate | GGPS1, COASY, FDPS | TRPV1 4825/4885ALDH1A1 2411/4885ALOX15 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.