SCHEMBL8622204

SCHEMBL8622204

CC(C)=CCCC(C)=CCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.58
ALDH1A1 P00352 1/20 0.45
ALOX15 P16050 1/20 0.45
DHODH Q02127 1/20 0.43
NFE2L2 Q16236 1/20 0.42
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
PGGT1B P53609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3092862 1.00 TRPV1 (0.58) TRPV1ALDH1A1ALOX15DHODHNFE2L2
SCHEMBL15246442 0.99 TRPV1 (0.56) TRPV1ALDH1A1ALOX15DHODHFNTA
SCHEMBL8058501 0.99 TRPV1 (0.56) TRPV1ALDH1A1ALOX15DHODHFNTA
SCHEMBL27733182 0.99 TRPV1 (0.56) TRPV1ALDH1A1ALOX15DHODHFNTA
SCHEMBL8058497 0.99 TRPV1 (0.56) TRPV1ALDH1A1ALOX15DHODHFNTA
SCHEMBL23802602 0.99 TRPV1 (0.56) TRPV1ALDH1A1ALOX15DHODHFNTA
SCHEMBL9417659 0.88 TRPV1 (0.50) TRPV1ALDH1A1DHODHFNTAFNTB
SCHEMBL9417658 0.88 TRPV1 (0.50) TRPV1ALDH1A1DHODHFNTAFNTB
SCHEMBL21436889 0.87 TRPV1 (0.53) TRPV1ALDH1A1ALOX15FNTAFNTB
SCHEMBL8712669 0.87 DHODH (0.50) TRPV1ALDH1A1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617747-B2 Cannabinoid analogs and methods for their preparation INMED PHARMACEUTICALS INC. (CA) 2026-05-05 US disclosed
US-20240117388-A1 ACYL ACTIVATING ENZYMES FOR PREPARATION OF CANNABINOIDS BAYMEDICA, INC. 2024-04-11 US disclosed
EP-4281553-A1 ACYL ACTIVATING ENZYMES FOR PREPARATION OF CANNABINOIDS BayMedica, Inc. (US) 2023-11-29 EP disclosed
US-11555211-B2 Recombinant production systems for prenylated polyketides of the cannabinoid family BAYMEDICA, INC. (US) 2023-01-17 US disclosed
WO-2022159589-A1 ACYL ACTIVATING ENZYMES FOR PREPARATION OF CANNABINOIDS BAYMEDICA, INC. (US) 2022-07-28 WO disclosed
US-20210403408-A1 CANNABINOID ANALOGS AND METHODS FOR THEIR PREPARATION INMED PHARMACEUTICALS INC. (CA) 2021-12-30 US disclosed
US-20210403959-A1 USE OF TYPE I AND TYPE II POLYKETIDE SYNTHASES FOR THE PRODUCTION OF CANNABINOIDS AND CANNABINOID ANALOGS BAYMEDICA, INC. 2021-12-30 US disclosed
EP-3873451-A1 CANNABINOID ANALOGS AND METHODS FOR THEIR PREPARATION BayMedica, Inc. (US) 2021-09-08 EP disclosed
US-20210040512-A1 RECOMBINANT PRODUCTION SYSTEMS FOR PRENYLATED POLYKETIDES OF THE CANNABINOID FAMILY BAYMEDICA, INC. 2021-02-11 US disclosed
US-10837031-B2 Recombinant production systems for prenylated polyketides of the cannabinoid family BAYMEDICA, INC. (US) 2020-11-17 US disclosed
WO-2020102430-A1 USE OF TYPE I AND TYPE II POLYKETIDE SYNTHASES FOR THE PRODUCTION OF CANNABINOIDS AND CANNABINOID ANALOGS BAYMEDICA, INC. (US) 2020-05-22 WO disclosed
EP-3622059-A1 RECOMBINANT PRODUCTION SYSTEMS FOR PRENYLATED POLYKETIDES OF THE CANNABINOID FAMILY BayMedica, Inc. (US) 2020-03-18 EP disclosed
CN-110869496-A Recombinant production system for pentenylated polyketones of the cannabinoid family 海湾医学公司 2020-03-06 CN disclosed
US-20180334692-A1 RECOMBINANT PRODUCTION SYSTEMS FOR PRENYLATED POLYKETIDES OF THE CANNABINOID FAMILY BAYMEDICA, INC. 2018-11-22 US disclosed
WO-2018209143-A1 RECOMBINANT PRODUCTION SYSTEMS FOR PRENYLATED POLYKETIDES OF THE CANNABINOID FAMILY BAYMEDICA, INC. (US) 2018-11-15 WO disclosed
EP-0711749-B1 Process for producing geranylgeraniol KURARAY CO (JP) 1998-05-20 EP disclosed
US-5663461-A HYDROLYSIS OF ESTER KURARAY CO., LTD. (JP) 1997-09-02 US disclosed
EP-0711749-A1 Process for producing geranylgeraniol KURARAY CO., LTD. (JP) 1996-05-15 EP disclosed
US-4514573-A ANTIVIRAL NISSHIN FLOUR MILLING CO., LTD. (JP) 1985-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617747-B2 Cannabinoid analogs and methods for their preparation CNR2, CNR1, FAAH TRPV1 119/4885ALDH1A1 1831/4885ALOX15 1446/4885
US-20210403408-A1 CANNABINOID ANALOGS AND METHODS FOR THEIR PREPARATION CNR1, CNR2, ERG28 TRPV1 591/4885ALDH1A1 4218/4885ALOX15 1832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.