⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41775 | 0.83 | TSHR (0.67) | — | |
| Formaldehyde SCHEMBL8673672 | 0.80 | TSHR (0.56) | — | |
| SCHEMBL29413339 | 0.79 | TSHR (0.62) | — | |
| SCHEMBL2644238 | 0.77 | CA2 (0.59) | — | |
| SCHEMBL31672218 | 0.76 | TSHR (0.59) | — | |
| Formic Acid SCHEMBL11392898 | 0.75 | TSHR (0.50) | — | |
| Oxalic Acid SCHEMBL30089202 | 0.75 | TSHR (0.58) | — | |
| SCHEMBL7670922 | 0.75 | TSHR (0.50) | — | |
| SCHEMBL746708 | 0.73 | ALDH1A1 (0.47) | — | |
| SCHEMBL8515272 | 0.73 | GFER (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026957-A | Three-component coupling method for aromatic trifluoroalkyl compound, conjugated olefin and nucleophilic reagent | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | claimed |
| CN-105623186-B | A method of it is moisture resistance hot to improve CEM-1 copper-clad laminate | 陕西生益科技有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-105623186-A | Method for improving moisture-resistant and heat-resistant performance of CEM-1 copper foil-clad laminate | SHENGYI TECH (SHAANXI) CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-104927308-A | Epoxy resin toughening agent based on cyclotriphosphazene six-arm star polymer and preparation method for epoxy resin toughening agent | UNIV JIANGNAN | 2015-09-23 | — | — | CN | claimed |
| CN-101977631-A | Polymer conjugate of physiologically active substance | NIPPON KAYAKU KK | 2011-02-16 | — | — | CN | claimed |
| US-20100056623-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2010-03-04 | — | — | US | claimed |
| EP-1575990-B1 | Solid phase bound PNA-dimers and their synthesis | APPLERA CORP (US) | 2009-11-18 | — | — | EP | claimed |
| EP-1841761-A4 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2008-10-29 | — | — | EP | claimed |
| EP-1841761-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2007-10-10 | — | — | EP | claimed |
| WO-2006080591-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2006-08-03 | — | — | WO | claimed |
| EP-1098925-B1 | POLYMER SUPPORTS CONTAINING POLYOXYALKYLENES | AVECIA LTD (GB) | 2006-05-10 | — | — | EP | claimed |
| US-20050261475-A1 | Solid-phase capture-release-tag methods for phosphoproteomic analyses | HARVARD MEDICAL SCHOOL (US) | 2005-11-24 | — | — | US | claimed |
| CN-1427743-A | Dosage forms of polymeric carriers, their use in organic chemical synthesis and process for producing said dosage forms | LONDBERK AS H (DK) | 2003-07-02 | — | — | CN | claimed |
| US-6395842-B1 | CROSSLINKED VIA PHENOXY ETHER LINKAGE; SOLID PHASE SYNTHESIS | AVECIA LIMITED (GB) | 2002-05-28 | — | — | US | claimed |
| EP-1098925-A1 | POLYMER SUPPORTS CONTAINING POLYOXYALKYLENES | Avecia Limited (GB) | 2001-05-16 | — | — | EP | claimed |
| WO-2000002953-A1 | POLYMER SUPPORTS CONTAINING POLYOXYALKYLENES | AVECIA LIMITED (GB) | 2000-01-20 | — | — | WO | claimed |
| US-5965598-A | PHOTOTHERAPEUTIC AND PHOTODIAGNOSTIC AGENTS AS FREE MOLECULES AND AS CONJUGATES WITH MACROMOLECULAR CARRIER MOLECULES | MOLTENI L. & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 1999-10-12 | — | — | US | claimed |
| EP-0906758-A1 | Zinc-phthalocyanines and corresponding conjugates, their preparation and use in photodynamic therapy and as diagnostic agents | MOLTENI L. & C. dei Fratelli Alitti Società di Esercizio S.P.A. (IT) | 1999-04-07 | — | — | EP | claimed |
| US-4727176-A | Hydroxymethylphenoxyphosphazenes and a process for producing same | THE DOW CHEMICAL COMPANY (US) | 1988-02-23 | — | — | US | claimed |
| CN-118026957-A | Three-component coupling method for aromatic trifluoroalkyl compound, conjugated olefin and nucleophilic reagent | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-110494157-A | Peptide and its peptide combinations for cancer immunotherapy | IMMATICS BIOTECHNOLOGIES GMBH | 2019-11-22 | — | — | CN | disclosed |
| CN-107216354-B | The preparation method of the six degree of functionality epoxy resin based on three phosphonitrile of ring | 西北工业大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-110198734-A | New type of peptides and peptide combinations for oophoroma and other cancer immunotherapies | 伊玛提克斯生物技术有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-104822702-B | α-MSH and γ-MSH analog | TXP制药股份有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109803981-A | Novel peptides and scaffolds for immunotherapy of head and neck squamous cell carcinoma and other cancers | 伊玛提克斯生物技术有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-109734777-A | For the new type of peptides of various cancer immunotherapies, peptide combinations and bracket | 伊玛提克斯生物技术有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109152813-A | As target and for the new type of peptides of gallbladder cancer and cholangiocarcinoma and other cancer immunotherapies, peptide combinations | 伊玛提克斯生物技术有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-109152825-A | Peptides, peptide compositions and cell-based drugs for immunotherapy of bladder cancer and other cancers | 伊玛提克斯生物技术有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-105623186-B | A method of it is moisture resistance hot to improve CEM-1 copper-clad laminate | 陕西生益科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109069587-A | The immunization therapy of melanoma and other cancers | 伊玛提克斯生物技术有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107987787-A | A kind of high flame-retardant polyurethane adhesive | 阜阳市龙建包装材料有限公司 | 2018-05-04 | — | — | CN | disclosed |
| US-20180016249-A1 | Methods of Treating an Overweight or Obese Subject | ZAFGEN INC (US) | 2018-01-18 | — | — | US | disclosed |
| CN-107434889-A | A kind of low cigarette EPDM clad | 西安近代化学研究所 | 2017-12-05 | — | — | CN | disclosed |
| EP-2258397-B1 | POLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | NIPPON KAYAKU KK (JP) | 2017-10-11 | — | — | EP | disclosed |
| CN-107216354-A | The preparation method of the six degree of functionality epoxy resin based on the phosphonitrile of ring three | 西北工业大学 | 2017-09-29 | — | — | CN | disclosed |
| US-9701651-B2 | Methods of treating an overweight or obese subject | ZAFGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2716651-B1 | PEPTIDE DERIVATIVES HAVING A SUPERIOR MOISTURIZING EFFECT AND USES THEREOF | INCOSPHARM CORP (KR) | 2017-06-21 | — | — | EP | disclosed |
| US-9656979-B2 | Methods of treating an overweight or obese subject | ZAFGEN, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| CN-106459167-A | Novel immunotherapy against several tumors of the blood, such as acute myeloid leukemia (AML) | 伊玛提克斯生物技术有限公司 | 2017-02-22 | — | — | CN | disclosed |
| US-9359401-B2 | Peptide analogues with an excellent moisturizing effect and use thereof | INCOSPHARM CORPORATION (KR) | 2016-06-07 | — | — | US | disclosed |
| CN-105623186-A | Method for improving moisture-resistant and heat-resistant performance of CEM-1 copper foil-clad laminate | SHENGYI TECH (SHAANXI) CO LTD | 2016-06-01 | — | — | CN | disclosed |
| US-20150361061-A1 | Methods of Treating an Overweight or Obese Subject | ZAFGEN, INC. | 2015-12-17 | — | — | US | disclosed |
| CN-104927308-A | Epoxy resin toughening agent based on cyclotriphosphazene six-arm star polymer and preparation method for epoxy resin toughening agent | UNIV JIANGNAN | 2015-09-23 | — | — | CN | disclosed |
| CN-102977188-B | GNRH (gonadotropin-releasing hormone) peptide variants | MEDICAL RES COUNCIL | 2015-07-15 | — | — | CN | disclosed |
| US-20150150857-A1 | Methods of Treating an Overweight or Obese Subject | ZAFGEN, INC. | 2015-06-04 | — | — | US | disclosed |
| US-8920788-B2 | High-molecular weight conjugate of physiologically active substances | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2014-12-30 | — | — | US | disclosed |
| CN-102186495-B | Methods of enhancing opsonophagocytosis in response to a pathogen | GOVERNMENT OF THE US SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES CT S FOR DISEASE | 2014-11-26 | — | — | CN | disclosed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20140113868-A1 | PEPTIDE ANALOGUES WITH AN EXCELLENT MOISTURIZING EFFECT AND USE THEREOF | INCOSPHARM CORPORATION (KR) | 2014-04-24 | — | — | US | disclosed |
| CN-102358748-B | Star chain transferring agent using cyclotriphosphazene as nucleus, and preparation method and application thereof | UNIV YUNNAN NORMAL | 2013-10-16 | — | — | CN | disclosed |
| CN-102083799-B | Benzimidazole derivatives used as FXR agonists | HOFFMANN LA ROCHE | 2013-10-16 | — | — | CN | disclosed |
| US-8518891-B2 | Chemotherapeutic conjugates and methods of use | HU LONGQIN (US) | 2013-08-27 | — | — | US | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8357653-B2 | System and method for inhibiting cellular proliferation with tachykinins | MAIER NATHAN C (US) | 2013-01-22 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| CN-101528918-B | Beta-alanine/alpha-ketoglutarate aminotransferase for producing 3-hydroxypropionic acid | NOVOZYMES AS | 2012-09-26 | — | — | CN | disclosed |
| US-8207293-B2 | Peptides derived from maurocalcine used as vectors for intracellular addressing of molecules of interest | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2012-06-26 | — | — | US | disclosed |
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| CN-102358748-A | Star chain transferring agent using cyclotriphosphazene as nucleus, and preparation method and application thereof | UNIV YUNNAN NORMAL | 2012-02-22 | — | — | CN | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120004162-A1 | Methods of Treating an Overweight or Obese Subject | ZAFGEN, INC. | 2012-01-05 | — | — | US | disclosed |
| CN-101076546-B | Polymeric beads for oligomer synthesis | ISIS PHARMACEUTICALS INC | 2011-10-26 | — | — | CN | disclosed |
| US-8034900-B2 | Water-soluble thioester and selenoester compounds and methods for making and using the same | AMYLIN PHARMACEUTICALS, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| CN-102186495-A | Methods of enhancing opsonophagocytosis in response to a pathogen | GOVERNMENT OF THE US SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES CT S FOR DISEASE | 2011-09-14 | — | — | CN | disclosed |
| US-8017584-B2 | Tumor associated antigens; fusion proteins; antibodies; keyhole limpet hemocyanin carrier enhances immunogenicity | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20110201754-A1 | High-Molecular Weight Conjugate Of Physiologically Active Substances | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-08-18 | — | — | US | disclosed |
| CN-102083799-A | Benzimidazole derivatives used as FXR agonists | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| CN-101977631-A | Polymer conjugate of physiologically active substance | NIPPON KAYAKU KK | 2011-02-16 | — | — | CN | disclosed |
| CN-101072791-B | S-Alkyl-thio Protecting Groups in Solid Phase Synthesis | LONZA AG | 2011-01-19 | — | — | CN | disclosed |
| US-20110009334-A1 | SYSTEM AND METHOD FOR INHIBITING CELLULAR PROLIFERATION WITH TACHYKININS | MAIER NATHAN C | 2011-01-13 | — | — | US | disclosed |
| EP-2258397-A1 | POLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | Nippon Kayaku Kabushiki Kaisha (JP) | 2010-12-08 | — | — | EP | disclosed |
| EP-2248895-A2 | Combination therapy associating a TGF-beta antagonist with a chemotherapeutic agent | Antisense Pharma GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| EP-2226637-A1 | Cross-linking agents on solid medium | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-09-08 | — | — | EP | disclosed |
| US-7754743-B2 | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20100160208-A1 | Pharmaceutical composition | ANTISENSE PHARMA GMBH | 2010-06-24 | — | — | US | disclosed |
| WO-2010065877-A2 | METHODS OF TREATING AN OVERWEIGHT OR OBESE SUBJECT | ZAFGEN CORPORATION (US) | 2010-06-10 | — | — | WO | disclosed |
| US-7728025-B2 | 2-heteroaryl-substituted benzimidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| CN-101712657-A | heteroarylcarbamoylbenzene derivative | BANYU PHARMA CO LTD | 2010-05-26 | — | — | CN | disclosed |
| CN-101023079-B | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE | 2010-05-05 | — | — | CN | disclosed |
| US-7691817-B2 | System and method for inhibiting cellular proliferation with tachykinins | MAIER NATHAN C | 2010-04-06 | — | — | US | disclosed |
| CN-101687911-A | Cysteine derivatives of antiviral peptides | CONJUCHEM BIOTECHNOLOGIES INC | 2010-03-31 | — | — | CN | disclosed |
| US-20100075927-A1 | CHEMOTHERAPEUTIC CONJUGATES AND METHODS OF USE | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100056623-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2010-03-04 | — | — | US | disclosed |
| CN-100591671-C | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMA CO LTD | 2010-02-24 | — | — | CN | disclosed |
| US-20100041660-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2010-02-18 | — | — | US | disclosed |
| EP-1122262-B1 | NEOVASCULAR-SPECIFIC PEPTIDES | OTSUKA PHARMA CO LTD (JP) | 2009-12-30 | — | — | EP | disclosed |
| US-7629362-B2 | 2-pyridine carboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| EP-1575990-B1 | Solid phase bound PNA-dimers and their synthesis | APPLERA CORP (US) | 2009-11-18 | — | — | EP | disclosed |
| CN-101528918-A | Beta-alanine/alpha-ketoglutarate aminotransferase for producing 3-hydroxypropionic acid | CARGILL INC (DK) | 2009-09-09 | — | — | CN | disclosed |
| US-20090142266-A1 | PEPTIDES DERIVED FROM MAUROCALCINE USED AS VECTORS FOR INTRACELLULAR ADDRESSING OF MOLECULES OF INTEREST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2009-06-04 | — | — | US | disclosed |
| CN-100480701-C | Perfluoro sulfonyl halides and related species as polymer support modifiers | GEN ELECTRIC HEALTH CARE CO LT (GB) | 2009-04-22 | — | — | CN | disclosed |
| US-20090018056-A1 | Heteroarylcarbamoylbenzene derivatives | MSD K.K. (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-1841761-A4 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2008-10-29 | — | — | EP | disclosed |
| US-7432287-B2 | Heteroarylcarbamoylbenzene derivative | BANYU PHARMECEUTICAL CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7425217-B2 | System and method for inhibiting cellular proliferation with tachykinins | CELONOVA BIOSCIENCES, INC. | 2008-09-16 | — | — | US | disclosed |
| EP-1932853-A1 | Novel depsipeptides and process for preparing same | Cubist Pharmaceutical Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008067495-A2 | CHEMOTHERAPEUTIC CONJUGATES AND METHODS OF USE | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080125374-A1 | GD3-MIMETIC PEPTIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| CN-101189253-A | Antiinfective lipopeptides | CUBIST PHARM INC (US) | 2008-05-28 | — | — | CN | disclosed |
| US-20080119395-A1 | Novel Depsipeptides and Process for Preparing Same | CUBIST PHARMACEUTICALS, INC. | 2008-05-22 | — | — | US | disclosed |
| CN-101166761-A | Peptide synthesizing method | LONZA AG (CH) | 2008-04-23 | — | — | CN | disclosed |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-7341994-B2 | GD3-mimetic peptides | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-20080051326-A1 | Antiinfective Lipopeptides | CUBIST PHARMACEUTICALS, INC. | 2008-02-28 | — | — | US | disclosed |
| CN-101094863-A | Peptides derived from maurocalcine used as vectors for intracellular addressing of molecules of interest | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2007-12-26 | — | — | CN | disclosed |
| CN-101076546-A | Polymeric beads for oligomer synthesis | ISIS PHARMACEUTICALS INC (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-101072791-A | S-Alkyl-thio Protecting Groups in Solid Phase Synthesis | LONZA AG (CH) | 2007-11-14 | — | — | CN | disclosed |
| EP-1841761-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2007-10-10 | — | — | EP | disclosed |
| CN-101031539-A | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORP (JP) | 2007-09-05 | — | — | CN | disclosed |
| CN-101023079-A | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | CN | disclosed |
| EP-1814588-A2 | ANTIINFECTIVE LIPOPEPTIDES | Cubist Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1631597-A4 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | GRYPHON THERAPEUTICS INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1616003-A4 | WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | GRYPHON THERAPEUTICS INC (US) | 2007-06-20 | — | — | EP | disclosed |
| EP-1783140-A2 | Neovascular-specific peptides | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-09 | — | — | EP | disclosed |
| CN-1926127-A | Novel 2-heteroaryl substituted benzimidazole derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-07 | — | — | CN | disclosed |
| EP-1279677-B1 | GD3-MIMETIC PEPTIDES | OTSUKA PHARMA CO LTD (JP) | 2007-03-07 | — | — | EP | disclosed |
| CN-1916020-A | Peptide antiangiogenic drugs | ABBOTT LAB (US) | 2007-02-21 | — | — | CN | disclosed |
| CN-1288166-C | Modified tumor antigen peptide and use thereof | JILIN SHENGYUAN TECHNOLOGY CO (CN) | 2006-12-06 | — | — | CN | disclosed |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
| WO-2006110185-A2 | ANTIINFECTIVE LIPOPEPTIDES | CUBIST PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | CUBIST PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |
| EP-1694840-A2 | COMBINATION THERAPY ASSOCIATING A TGF-BETA ANTAGONIST WITH A CHEMOTHERAPEUTIC AGENT | Antisense Pharma GmbH (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20060173159-A1 | Water-soluble thioester and selenoester compounds and methods for making and using the same | ASTRAZENECA PHARMACEUTICALS LP | 2006-08-03 | — | — | US | disclosed |
| WO-2006080591-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2006-08-03 | — | — | WO | disclosed |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | MSD K.K. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-7060678-B2 | Peptides comprising furanoid sugar amino acids for the treatment of cancer | DABUR RESEARCH FOUNDATION (IN) | 2006-06-13 | — | — | US | disclosed |
| EP-1315738-A4 | EXTENDED NATIVE CHEMICAL LIGATION | GRYPHON THERAPEUTICS INC (US) | 2006-06-07 | — | — | EP | disclosed |
| US-7053214-B2 | β-sheet mimetics and composition and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| CN-1777589-A | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMA CO LTD (JP) | 2006-05-24 | — | — | CN | disclosed |
| EP-1098925-B1 | POLYMER SUPPORTS CONTAINING POLYOXYALKYLENES | AVECIA LTD (GB) | 2006-05-10 | — | — | EP | disclosed |
| US-20060084653-A1 | Beta-sheet mimetics and composition and methods relating thereto | MYRIAD GENETICS, INCORPORATED (US) | 2006-04-20 | — | — | US | disclosed |
| EP-1482941-A4 | BETA-SHEET MIMETICS AND COMPOSITION AND METHODS RELATING THERETO | MYRIAD GENETICS INC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20060058226-A1 | Gd3-mimetic peptides | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1631597-A2 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | Gryphon Therapeutics, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| CN-1240714-C | Chirality peptide antigen and compon of bacterin based on core sequence of mucin 1 | SHENGYUAN SCI TECH CO LTD JILI (CN) | 2006-02-08 | — | — | CN | disclosed |
| EP-1616875-A1 | GD3-mimetic peptides | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
| CN-1721436-A | Modified tumor antigen peptide and use thereof | JILIN SHENGYUAN TECHNOLOGY CO (CN) | 2006-01-18 | — | — | CN | disclosed |
| EP-1616003-A1 | WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Gryphon Therapeutics, Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1423414-A4 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARM INC (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1600442-A1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20050261475-A1 | Solid-phase capture-release-tag methods for phosphoproteomic analyses | HARVARD MEDICAL SCHOOL (US) | 2005-11-24 | — | — | US | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-20050197289-A1 | System and method for inhibiting cellular proliferation with tachykinins | Maier, Nathan | 2005-09-08 | — | — | US | disclosed |
| WO-2005059133-A2 | COMBINATION THERAPY ASSOCIATING A TGF-BRETA ANTAGONIST WITH A CHEMIOTHERAPEUTIC AGENT | ANTISENSE PHARMA GMBH (DE) | 2005-06-30 | — | — | WO | disclosed |
| EP-1531849-A2 | SYSTEM AND METHOD FOR INHIBITING CELLULAR PROLIFERATION WITH TACHYKININS | Maier, Nathan C. (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20050032707-A1 | Novel peptides comprising furanoid sugar amino acids for the treatment of cancer | DABUR RESEARCH FOUNDATION | 2005-02-10 | — | — | US | disclosed |
| EP-1299391-B1 | INDOLINOSPIROPYRAN COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | JOHNSON & JOHNSON VISION CARE (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2004105685-A2 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | GRYPHON THERAPEUTICS, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| EP-1482941-A1 | BETA-SHEET MIMETICS AND COMPOSITION AND METHODS RELATING THERETO | Myriad Pharmaceuticals, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | disclosed |
| CN-1173992-C | Hybrid peptide with vascularization inhibiting activity | 吉林圣元科技有限责任公司 | 2004-11-03 | — | — | CN | disclosed |
| US-6803471-B2 | USEFUL AS PHOTOCHROMIC COMPOUNDS; COVALENTLY ATTACHED TO WANG RESINS AND METHOD OF ATTACHING; OPHTHALMIC LENSES | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-12 | — | — | US | disclosed |
| CN-1167670-C | Aryl carboxylic acid and tetrazole derivant | - | 2004-09-22 | — | — | CN | disclosed |
| US-20040175763-A1 | Crohn's disease antibody-binding peptide and method of examining crohn's disease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
| CN-1163477-C | Substituted beta-alanines | — | 2004-08-25 | — | — | CN | disclosed |
| CN-1524181-A | Perfluorosulfonyl halides and related materials as polymer support modifiers | ��Ĭɳķ��������˾ | 2004-08-25 | — | — | CN | disclosed |
| WO-2004061094-A1 | WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | GRYPHON THERAPEUTICS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-6753310-B1 | ANGIOGENESIS-SPECIFIC PEPTIDES; DRUG DELIVERY; ANTICARCINOGENIC AGENTS; CANCER DIAGNOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |
| CN-1152962-C | Antiangiogenic peptides derived from plasminogen, its coded polynucleotide and method of inhibiting vascularization | ���Ͽع�����˾ | 2004-06-09 | — | — | CN | disclosed |
| EP-1423414-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | Cubist Pharmaceuticals, Inc. (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1409519-A1 | LIPID-PEPTIDE CONJUGATES FOR TREATMENT OF CANCER | Dabur Research Foundation (IN) | 2004-04-21 | — | — | EP | disclosed |
| US-20040057945-A1 | System and method for inhibiting cellular proliferation with tachykinins | Maier, Nathan | 2004-03-25 | — | — | US | disclosed |
| CN-1480463-A | Chirality peptide antigen and compon of bacterin based on core sequence of mucin 1 | 吉林圣元科技有限责任公司 | 2004-03-10 | — | — | CN | disclosed |
| EP-1391462-A1 | CROHN'S DISEASE ANTIBODY-BINDING PEPTIDE AND METHOD OF EXAMINING CROHN'S DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-25 | — | — | EP | disclosed |
| WO-2004011424-A2 | SIDE CHAIN ANCHORED THIOESTER AND SELENOESTER GENERATORS | GRYPHON THERAPEUTICS, INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
| WO-2004000208-A2 | SYSTEM AND METHOD FOR INHIBITING CELLULAR PROLIFERATION WITH TACHYKININS | MAIER NATHAN C (US) | 2003-12-31 | — | — | WO | disclosed |
| CN-1452632-A | Extended native chemical ligation | GRYPHON SCIENCES INC (US) | 2003-10-29 | — | — | CN | disclosed |
| WO-2003068237-A1 | BETA-SHEET MIMETICS AND COMPOSITION AND METHODS RELATING THERETO | MYRIAD GENETICS, INC. (US) | 2003-08-21 | — | — | WO | disclosed |
| CN-1427743-A | Dosage forms of polymeric carriers, their use in organic chemical synthesis and process for producing said dosage forms | LONDBERK AS H (DK) | 2003-07-02 | — | — | CN | disclosed |
| US-6586187-B1 | 2-benzyloxycarbonylamino-3-(2-(4-(2-(3-benzylureido)-ethyl) -piperazin-1-yl)acetylamino)-propionic acid, for example; method of synthesis using Wang resins; various uses including anticancer, antiinflammatory and antiviral agents | WYETH | 2003-07-01 | — | — | US | disclosed |
| EP-1315738-A1 | EXTENDED NATIVE CHEMICAL LIGATION | Gryphon Therapeutics, Inc. (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20030083240-A1 | Novel depsipeptides and process for preparing same | CUBIST PHARMACEUTICALS, INC. | 2003-05-01 | — | — | US | disclosed |
| EP-1299391-A2 | INDOLINOSPIROPYRAN COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | Johnson & Johnson Vision Care, Inc. (US) | 2003-04-09 | — | — | EP | disclosed |
| CN-1398896-A | Hybrid peptide with vascularization inhibiting activity | JINLIN SHENGYUAN SCIENCE & TEC (CN) | 2003-02-26 | — | — | CN | disclosed |
| US-6525061-B1 | Combinatorial libraries for drug discovery;4-((6-bromo-4-oxo-1,4-dihydroquinazolin-2-yl)amino)b enzoic acid, | WYETH | 2003-02-25 | — | — | US | disclosed |
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |
| US-6521753-B1 | Indolinospiropyran compounds and methods for their manufacture | JOHNSON & JOHNSON VISION CARE, INC. | 2003-02-18 | — | — | US | disclosed |
| EP-1279677-A1 | GD3-MIMETIC PEPTIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-1240239-A1 | COLOURED POLYPHENOXYDENDRIMERS, NOVEL SOLUBLE SUPPORTS, METHOD FOR PREPARING SAME AN USE IN ORGANIC SYNTHESIS | Aventis Pharma S.A. (FR) | 2002-09-18 | — | — | EP | disclosed |
| US-20020087010-A1 | Indolinospiropyran compounds and methods for their manufacture | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2002-07-04 | — | — | US | disclosed |
| US-6395842-B1 | CROSSLINKED VIA PHENOXY ETHER LINKAGE; SOLID PHASE SYNTHESIS | AVECIA LIMITED (GB) | 2002-05-28 | — | — | US | disclosed |
| US-20020049320-A1 | 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
| WO-2002020557-A1 | EXTENDED NATIVE CHEMICAL LIGATION | GRYPHON THERAPEUTICS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |
| WO-2002010193-A1 | LIPID-PEPTIDE CONJUGATES FOR TREATMENT OF CANCER | DABUR RESEARCH FOUNDATION (IN) | 2002-02-07 | — | — | WO | disclosed |
| WO-2001092265-A2 | INDOLINOSPIROPYRAN COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| US-6287794-B1 | Factor Vlla inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-09-11 | — | — | US | disclosed |
| CN-1311796-A | Peptide antiangiogenic agents | ABBOTT LAB (US) | 2001-09-05 | — | — | CN | disclosed |
| EP-1122262-A1 | NEOVASCULAR-SPECIFIC PEPTIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| WO-2001038424-A1 | COLOURED POLYPHENOXYDENDRIMERS, NOVEL SOLUBLE SUPPORTS, METHOD FOR PREPARING SAME AN USE IN ORGANIC SYNTHESIS | AVENTIS PHARMA S.A. (FR) | 2001-05-31 | — | — | WO | disclosed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-1098925-A1 | POLYMER SUPPORTS CONTAINING POLYOXYALKYLENES | Avecia Limited (GB) | 2001-05-16 | — | — | EP | disclosed |
| CN-1283181-A | Substituted beta-alanines | AWONGTISFAMA CO LTD (GB) | 2001-02-07 | — | — | CN | disclosed |
| WO-2000061545-A1 | METHODS FOR SOLID PHASE COMBINATORIAL SYNTHESIS OF INTEGRIN INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-19 | — | — | WO | disclosed |
| US-6127191-A | SOLID SUPPORT HAVING PLURALITY OF PENDANT SCAFFOLD MOIETIES COVALENTLY ATTACHED; FOR SYNTHESIS OF BIOACTIVE MOLECULES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-10-03 | — | — | US | disclosed |
| CN-1266054-A | Aryl carboxylic acid and tetrazole derivant | HOFFMANN LA ROCHE (CH) | 2000-09-13 | — | — | CN | disclosed |
| CN-1264425-A | Syncytial respiratory virus epitopes and antibodies comprising them, useful in diagnosis and therapy | PF MEDICAMENT (FR) | 2000-08-23 | — | — | CN | disclosed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | disclosed |
| WO-2000002953-A1 | POLYMER SUPPORTS CONTAINING POLYOXYALKYLENES | AVECIA LIMITED (GB) | 2000-01-20 | — | — | WO | disclosed |
| US-5965598-A | PHOTOTHERAPEUTIC AND PHOTODIAGNOSTIC AGENTS AS FREE MOLECULES AND AS CONJUGATES WITH MACROMOLECULAR CARRIER MOLECULES | MOLTENI L. & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 1999-10-12 | — | — | US | disclosed |
| CN-1045005-C | Novel bisoxadiazolidine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1999-09-08 | — | — | CN | disclosed |
| US-5932743-A | Methods for the solid phase synthesis of substituted indole compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| CN-1223690-A | Antiangiogenic peptides derived from plasminogen, its coded polynucleotide and method of inhibiting vascularization | ABBOTT LAB (US) | 1999-07-21 | — | — | CN | disclosed |
| EP-0906758-A1 | Zinc-phthalocyanines and corresponding conjugates, their preparation and use in photodynamic therapy and as diagnostic agents | MOLTENI L. & C. dei Fratelli Alitti Società di Esercizio S.P.A. (IT) | 1999-04-07 | — | — | EP | disclosed |
| WO-1999009007-A1 | SOLID PHASE SYNTHESIS OF 2,3-DISUBSTITUTED INDOLE COMPOUNDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-25 | — | — | WO | disclosed |
| CN-1202888-A | Isoquinoline derivatives and isoquinoline combinatorial libraries | TORREY PINES INST (US) | 1998-12-23 | — | — | CN | disclosed |
| US-5817617-A | INHIBIT ADHESION OF LEUKOCYTES TO ENDOTHELIA AND EPITHELIA | THE ROCKEFELLER UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5770691-A | MATRIX METALLOPROTEASE, DECAPEPTIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1998024760-A1 | AMINOBENZENEDICARBOXYLIC ACID-BASED COMBINATORIAL LIBRARIES | GRAYBILL TODD L (US) | 1998-06-11 | — | — | WO | disclosed |
| WO-1997000084-A1 | NONIMMUNOGENIC MHC-BLOCKING PEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1997-01-03 | — | — | WO | disclosed |
| CN-1137275-A | O-aryl O-alkyl O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity | MERCK & CO INC (US) | 1996-12-04 | — | — | CN | disclosed |
| CN-1122133-A | Novel bis-oxadiazolidine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-05-08 | — | — | CN | disclosed |
| EP-0708751-A1 | SYNTHESIS OF COMBINATORIAL ARRAYS OF ORGANIC COMPOUNDS THROUGH THE USE OF MULTIPLE COMPONENT COMBINATORIAL ARRAY SYNTHESES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0668871-A1 | AMINO-ACID SEQUENCE HOMOLOGIES BETWEEN SELECTINS AND B. PERTUSSIS TOXIN-PEPTIDESDERIVED THERFROM, ANTIBODIES THERETO AND PHARMACEUTICAL COMPOSITIONS | THE ROCKEFELLER UNIVERSITY (US) | 1995-08-30 | — | — | EP | disclosed |
| WO-1995002566-A1 | SYNTHESIS OF COMBINATORIAL ARRAYS OF ORGANIC COMPOUNDS THROUGH THE USE OF MULTIPLE COMPONENT COMBINATORIAL ARRAY SYNTHESES | ONTOGEN CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| WO-1994002510-A2 | ANALOGS OF PTH | SANDOZ LTD. (CH) | 1994-02-03 | — | — | WO | disclosed |
| WO-1992019646-A1 | ANALOG OF ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE (ELAM) | THE ROCKEFELLER UNIVERSITY (US) | 1992-11-12 | — | — | WO | disclosed |
| US-4604386-A | CONTROL OF GRAMPOSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |