Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25971939 | 0.93 | DPP7 (0.45) | EPHX2GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL25831517 | 0.88 | KMT2A (0.42) | EPHX2GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL23807034 | 0.86 | EPHX1 (0.50) | EPHX2RRM1DPP7MMP8ACHE | |
| SCHEMBL21107013 | 0.84 | MMP8 (0.49) | RRM1DPP7MEN1KMT2AMMP8 | |
| SCHEMBL22794783 | 0.84 | MMP8 (0.49) | RRM1DPP7MEN1KMT2AMMP8 | |
| SCHEMBL22799828 | 0.84 | DPP7 (0.50) | EPHX2RRM1DPP7MEN1KMT2A | |
| SCHEMBL23806827 | 0.84 | GNAI3 (0.47) | EPHX2GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL21107012 | 0.83 | KMT2A (0.46) | EPHX2GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL21105998 | 0.83 | KMT2A (0.44) | EPHX2GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL23945209 | 0.82 | KMT2A (0.42) | EPHX2GNAI3GNAO1GNAI1RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117889-B1 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2021-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11117889-B1 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | EPHX2 1890/4885GNAI3 1664/4885GNAO1 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.