Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | PIP5K1C | O60331 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.34 |
| ▸ | ACACA | Q13085 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028513 | 0.89 | ITK (0.44) | ITKPIP5K1CKDRMEN1KMT2A | |
| SCHEMBL12028453 | 0.87 | ITK (0.47) | ITKPIP5K1CRAB9ANPC1KDR | |
| SCHEMBL12028506 | 0.85 | ITK (0.49) | ITKPIP5K1CRAB9ANPC1KDR | |
| SCHEMBL22899288 | 0.85 | ITK (0.45) | ITKPIP5K1CKDRACACBACACA | |
| SCHEMBL23808289 | 0.85 | ITK (0.48) | ITKPIP5K1CKDRMEN1KMT2A | |
| SCHEMBL12028510 | 0.85 | ITK (0.48) | ITKPIP5K1CRAB9ANPC1KDR | |
| SCHEMBL12028443 | 0.83 | ITK (0.56) | ITKPIP5K1CKDR | |
| SCHEMBL24671204 | 0.83 | ITK (0.49) | ITKPIP5K1CMEN1KMT2AACACB | |
| SCHEMBL30801267 | 0.83 | ITK (0.49) | ITKPIP5K1CMEN1KMT2AACACB | |
| SCHEMBL12028517 | 0.82 | ITK (0.50) | ITKPIP5K1CKDRKMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284627-A1 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284627-A1 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | IDO1, IDO2, INMT | ITK 732/4885PIP5K1C 2200/4885RAB9A 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.