SCHEMBL2380862

SCHEMBL2380862

CC1(C)c2ccccc2-c2ccc(-c3c4ccc(Br)cc4c(-c4ccc5c(c4)C(C)(C)c4ccccc4-5)c4cc5c(cc34)-c3ccccc3C5(C)C)cc21

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.37
RXRA P19793 2/20 0.32
ALK Q9UM73 1/20 0.31
PTPRC P08575 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2378738 0.95 PDK2 (0.40) PDK2PTPRC
SCHEMBL490874 0.95 PDK2 (0.38) PDK2RXRAALKPTPRC
SCHEMBL2379782 0.91 ALDH1A1 (0.35) PDK2RXRAALK
SCHEMBL2380626 0.91 DPP4 (0.36) PDK2RXRAALK
SCHEMBL2381917 0.90 CYP2A6 (0.37) PDK2ALK
SCHEMBL12560764 0.89 PDK2 (0.43) PDK2PTPRC
SCHEMBL4234951 0.89 PDK2 (0.35) PDK2
SCHEMBL2380452 0.87 PDK2 (0.32) PDK2
SCHEMBL13819625 0.86 DPP4 (0.36) PDK2
SCHEMBL12560710 0.86 PDK2 (0.37) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014104666-A1 INK COMPOSITION FOR ORGANIC ELECTRONIC ELEMENT, AND ORGANIC ELECTRONIC ELEMENT USING SAME 주식회사 두산 (KR) 2014-07-03 WO disclosed
WO-2014104666-A1 INK COMPOSITION FOR ORGANIC ELECTRONIC ELEMENT, AND ORGANIC ELECTRONIC ELEMENT USING SAME 주식회사 두산 (KR) 2014-07-03 WO disclosed
US-8525158-B2 Anthracene derivative and organic electroluminescence element using the same DOOSAN CORPORATION (KR) 2013-09-03 US disclosed
US-8395144-B2 Anthracene derivatives and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2013-03-12 US disclosed
US-8395144-B2 Anthracene derivatives and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2013-03-12 US disclosed
US-20110210320-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING THE SAME DOOSAN CORPORATION (KR) 2011-09-01 US disclosed
US-20110057182-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2011-03-10 US disclosed
US-20110057182-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2011-03-10 US disclosed
US-20110057182-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2011-03-10 US disclosed
WO-2010027181-A2 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING THE SAME 주식회사 두산 (KR) 2010-03-11 WO disclosed
WO-2009139580-A2 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2009-11-19 WO disclosed
WO-2009139580-A2 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2009-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110057182-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME TRPA1, AHR, ORAI2 PDK2 836/4885RXRA 1370/4885ALK 231/4885
US-20110210320-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING THE SAME KCNJ2, KCNJ1, BRD4 PDK2 646/4885RXRA 2307/4885ALK 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.