Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061123 | 0.88 | ALDH1A1 (0.53) | HSD17B10HPGDPTPRBCA12CA1 | |
| SCHEMBL6168725 | 0.88 | KDM4E (0.46) | HSD17B10HPGDPTPRBCA12CA1 | |
| SCHEMBL18415515 | 0.86 | ALDH1A1 (0.55) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL10682760 | 0.81 | KDM4E (0.68) | HSD17B10HPGDCA12CA1CA2 | |
| SCHEMBL18053313 | 0.80 | HPGD (0.54) | HSD17B10HPGDPTPRBALDH1A1 | |
| SCHEMBL31309509 | 0.79 | CA12 (0.47) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL10676568 | 0.79 | MAPT (0.49) | HSD17B10HPGDCA12CA1CA2 | |
| SCHEMBL2605591 | 0.79 | CA1 (0.60) | HSD17B10HPGDCA12CA1CA2 | |
| SCHEMBL20194445 | 0.79 | ALDH1A1 (0.49) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL18415478 | 0.79 | MAPT (0.48) | HSD17B10HPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326715-B1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | CE PHARM CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |