Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | XDH | P47989 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14448996 | 0.89 | LMNA (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL15958202 | 0.89 | CA12 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL10832764 | 0.88 | CA1 (0.58) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29710347 | 0.88 | CA12 (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31401490 | 0.88 | CA1 (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31161744 | 0.88 | KDM4E (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL18969524 | 0.88 | KMT2A (0.51) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14077650 | 0.88 | KDM4E (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL19357846 | 0.88 | CA12 (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL15957687 | 0.86 | CA12 (0.47) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213016-A1 | Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same | ETNA-TEC, LTD. | 2022-07-07 | — | — | US | disclosed |
| US-9623046-B2 | Amphiphilic Janus-dendrimers | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-04-18 | — | — | US | disclosed |
| US-9464232-B2 | Compound, liquid crystal composition, polymer material, and film | FUJIFILM CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| US-9433626-B2 | Pyrido[4,3-B]indole and pyrido[3,4-B]indole derivatives and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9434747-B2 | Methods of treating diabetes | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9383491-B2 | Retardation film, polarizing plate, and liquid crystal display | FUJIFILM CORPORATION (JP) | 2016-07-05 | — | — | US | disclosed |
| US-20160131809-A1 | PHASE DIFFERENCE FILM, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20150335654-A1 | PYRIDO [4,3-B] INDOLE AND PYRIDO [3,4-B] INDOLE DERIVATIVES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2015-11-26 | — | — | US | disclosed |
| US-9193728-B2 | Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-9034865-B2 | Pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-05-19 | — | — | US | disclosed |
| US-20100239522-A1 | CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2010-09-23 | — | — | US | disclosed |
| US-20100099041-A1 | POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | GEORGIA TECH RESEARCH CORPORATION | 2009-03-12 | — | — | US | disclosed |
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
| WO-2007000550-A2 | NOVEL INDOLINE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2007-01-04 | — | — | WO | disclosed |
| CN-1392796-A | Polyhydroxylated benzene-containing compounds | ARCH DEV CORP (US) | 2003-01-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213016-A1 | Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same | ALKBH3, FTO, ALK | CA1 919/4885CA2 2671/4885CA12 1388/4885 |
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | CA1 4641/4885CA2 4221/4885CA12 4875/4885 |
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | SLC9A3, SLC18A2, SLC9A2 | CA1 510/4885CA2 390/4885CA12 228/4885 |
| US-20100239522-A1 | CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY | MSH2, MSH6, PMS2 | CA1 2277/4885CA2 3610/4885CA12 4425/4885 |
| US-20150335654-A1 | PYRIDO [4,3-B] INDOLE AND PYRIDO [3,4-B] INDOLE DERIVATIVES AND METHODS OF USE | HTR3B, HTR4, HTR2C | CA1 3101/4885CA2 4155/4885CA12 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.