Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 11/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445674 | 0.89 | MAPT (0.35) | CNR2CNR1MEN1MAPTRAB9A | |
| SCHEMBL26037890 | 0.82 | NR3C1 (0.35) | NR3C1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL17943466 | 0.80 | CNR1 (0.31) | CNR2CNR1 | |
| SCHEMBL12335154 | 0.72 | MEN1 (0.45) | SLC2A1SLC2A2SLC2A3NR3C1PDE8B | |
| SCHEMBL22304936 | 0.71 | SLC16A3 (0.35) | CNR2SLC16A3SLC16A1CNR1PDE8B | |
| SCHEMBL13748881 | 0.71 | GRM2 (0.37) | CNR2CNR1MAPT | |
| SCHEMBL284087 | 0.71 | CNR2 (0.40) | SLC2A1SLC2A2SLC2A3CNR2SLC16A3 | |
| SCHEMBL22304933 | 0.70 | CNR2 (0.34) | NR3C1CNR2SLC16A3SLC16A1CNR1 | |
| SCHEMBL21960869 | 0.68 | L3MBTL1 (0.42) | SLC2A1SLC2A2SLC2A3NR3C1CNR2 | |
| SCHEMBL24758178 | 0.68 | NR3C1 (0.41) | SLC2A1SLC2A2SLC2A3NR3C1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283138-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | VANDERBILT UNIVERSITY | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283138-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, BCL9 | SLC2A1 2589/4885SLC2A2 2806/4885SLC2A3 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.