⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14152505 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3660487 | 0.98 | L3MBTL1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3061315 | 0.98 | L3MBTL1 (0.31) | — | |
| SCHEMBL678742 | 0.80 | — | — | |
| SCHEMBL17275380 | 0.79 | ADRA2A (0.32) | — | |
| SCHEMBL28623791 | 0.79 | ADRA2A (0.32) | — | |
| SCHEMBL14152223 | 0.77 | CNR2 (0.36) | — | |
| SCHEMBL14151887 | 0.77 | CNR2 (0.36) | — | |
| SCHEMBL18618359 | 0.76 | — | — | |
| SCHEMBL21536856 | 0.76 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919901-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-10919901-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200247811-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION | 2020-08-06 | — | — | US | disclosed |
| US-20200247811-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION | 2020-08-06 | — | — | US | disclosed |
| US-10472367-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE INCORPORATION (US) | 2019-11-12 | — | — | US | disclosed |
| US-10472367-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE INCORPORATION (US) | 2019-11-12 | — | — | US | disclosed |
| US-20180370977-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE HOLDINGS CORPORATION | 2018-12-27 | — | — | US | disclosed |
| US-9988387-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2018-06-05 | — | — | US | disclosed |
| US-9988387-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2018-06-05 | — | — | US | disclosed |
| US-9988387-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2018-06-05 | — | — | US | disclosed |
| US-9221824-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221824-B2 | Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| EP-2410857-B1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME (US) | 2014-01-29 | — | — | EP | disclosed |
| US-20130345224-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION (US) | 2013-12-26 | — | — | US | disclosed |
| US-8487096-B2 | Imidazo[1,2-B][1,2,4]triazines as C-MET inhibitors | INCYTE CORPORATION (US) | 2013-07-16 | — | — | US | disclosed |
| US-8487096-B2 | Imidazo[1,2-B][1,2,4]triazines as C-MET inhibitors | INCYTE CORPORATION (US) | 2013-07-16 | — | — | US | disclosed |
| US-8487096-B2 | Imidazo[1,2-B][1,2,4]triazines as C-MET inhibitors | INCYTE CORPORATION (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110212967-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110212967-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110212967-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION (US) | 2011-09-01 | — | — | US | disclosed |