Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.43 |
| ▸ | CTSS | P25774 | 18/20 | 0.35 |
| ▸ | CTSB | P07858 | 17/20 | 0.35 |
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616543 | 0.88 | CTSL (0.43) | CTSLCTSSCTSBCTSK | |
| SCHEMBL20341765 | 0.87 | CTSL (0.44) | CTSLCTSSCTSBCTSK | |
| SCHEMBL23810246 | 0.85 | CTSL (0.45) | CTSLCTSSCTSBCTSK | |
| SCHEMBL23810255 | 0.85 | CTSL (0.45) | CTSLCTSSCTSBCTSK | |
| SCHEMBL18616529 | 0.84 | CTSL (0.43) | CTSLCTSSCTSBCTSK | |
| SCHEMBL20341781 | 0.79 | CTSL (0.40) | CTSLCTSSCTSBCTSK | |
| SCHEMBL23810283 | 0.77 | CTSL (0.38) | CTSLCTSSCTSBCTSK | |
| SCHEMBL18615940 | 0.73 | CTSL (0.45) | CTSLCTSSCTSBCTSK | |
| SCHEMBL18616546 | 0.73 | CTSL (0.45) | CTSLCTSSCTSBCTSK | |
| SCHEMBL18616651 | 0.73 | CTSL (0.45) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |