Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341833 | 0.91 | CTSS (0.36) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL23810272 | 0.88 | CTSS (0.34) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL23810313 | 0.88 | TACR2 (0.33) | TACR2CTSSCTSK | |
| SCHEMBL20341777 | 0.86 | TACR2 (0.32) | TACR2 | |
| SCHEMBL18616609 | 0.84 | CTSL (0.45) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL18615883 | 0.84 | CTSL (0.45) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL20341824 | 0.84 | CTSS (0.34) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL18615931 | 0.79 | CTSS (0.36) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL18615930 | 0.77 | CTSL (0.46) | TACR2CTSSCTSKCTSLCTSB | |
| SCHEMBL20341822 | 0.77 | CTSS (0.32) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |