Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 5/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1523537 | 0.99 | FOLH1 (0.43) | FOLH1HRH4HRH3ALDH1A1CYP19A1 | |
| SCHEMBL12648750 | 0.98 | FOLH1 (0.44) | FOLH1HRH4HRH3ALDH1A1CYP19A1 | |
| Hydrochloric Acid SCHEMBL1523213 | 0.97 | FOLH1 (0.43) | FOLH1HRH4HRH3ALDH1A1CYP19A1 | |
| Hydrochloric Acid SCHEMBL1523643 | 0.97 | FOLH1 (0.43) | FOLH1HRH4HRH3ALDH1A1CYP19A1 | |
| Hydrochloric Acid SCHEMBL1523934 | 0.97 | FOLH1 (0.43) | FOLH1HRH4HRH3ALDH1A1CYP19A1 | |
| SCHEMBL12595385 | 0.97 | FOLH1 (0.42) | FOLH1HRH4HRH3ALDH1A1CYP19A1 | |
| SCHEMBL12764913 | 0.94 | FOLH1 (0.42) | FOLH1HRH4HRH3ALDH1A1GBA1 | |
| SCHEMBL12648794 | 0.86 | EPHX2 (0.48) | HRH4HRH3GBA1EPHX2 | |
| SCHEMBL12595319 | 0.86 | EPHX2 (0.48) | HRH4HRH3GBA1EPHX2 | |
| SCHEMBL12648747 | 0.86 | EPHX2 (0.48) | HRH4HRH3GBA1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283107-A1 | Methods to Expand the Spectrum of Gram-Positive Antibiotics | UNIV NORTH CAROLINA STATE (US) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283107-A1 | Methods to Expand the Spectrum of Gram-Positive Antibiotics | RPN2, RPN1, MGAM | FOLH1 1214/4885HRH4 3089/4885HRH3 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.