Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481372 | 0.90 | LMNA (0.43) | LMNAGAACA12CA1CA2 | |
| SCHEMBL26079396 | 0.86 | GAA (0.50) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL9387072 | 0.86 | GAA (0.50) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL20510702 | 0.86 | LMNA (0.40) | LMNAGAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8536341 | 0.85 | GAA (0.40) | LMNAGAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL27547194 | 0.85 | GAA (0.49) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL1982542 | 0.85 | GAA (0.49) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL24722323 | 0.85 | LMNA (0.37) | LMNAGAACA12CA1CA2 | |
| SCHEMBL21201581 | 0.84 | LMNA (0.39) | LMNAGAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL18081555 | 0.83 | LMNA (0.38) | LMNAGAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283125-A1 | CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | FORTVITA BIOLOGICS LIMITED (CN) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283125-A1 | CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | TOP2A, TOP1, XPA | LMNA 986/4885GAA 1021/4885PAOX 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.