Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 3/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20510702 | 0.98 | LMNA (0.40) | LMNAGAATSHRNFKB1PMP22 | |
| SCHEMBL8481372 | 0.94 | LMNA (0.43) | LMNAGAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL26079396 | 0.86 | GAA (0.50) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL27362262 | 0.86 | LMNA (0.38) | LMNAGAATSHRKMT2AMEN1 | |
| SCHEMBL9387072 | 0.86 | GAA (0.50) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL8536341 | 0.85 | GAA (0.40) | LMNAGAATSHRKMT2AMEN1 | |
| SCHEMBL1982542 | 0.85 | GAA (0.49) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL27547194 | 0.85 | GAA (0.49) | LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL23813764 | 0.84 | LMNA (0.39) | LMNAGAATSHRKMT2AMEN1 | |
| SCHEMBL24722323 | 0.82 | LMNA (0.37) | LMNAGAATSHRKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10365290-B2 | Multifunctional protein molecular weight ladders | LI-COR, INC. (US) | 2019-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10365290-B2 | Multifunctional protein molecular weight ladders | MPEG1, PSMB11, ACP1 | LMNA 1465/4885GAA 2167/4885TSHR 3857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.