Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25616185 | 0.72 | NOS3 (0.33) | NOS3NOS2ADORA2AADORA2BADORA1 | |
| SCHEMBL23815922 | 0.70 | ADORA2A (0.33) | ADORA2AADORA2BADORA1 | |
| SCHEMBL23816132 | 0.63 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL24204653 | 0.61 | — | — | |
| SCHEMBL25616201 | 0.60 | ADORA2A (0.33) | ADORA2AADORA2BADORA1 | |
| SCHEMBL13866835 | 0.59 | RXFP1 (0.35) | — | |
| SCHEMBL14933945 | 0.58 | — | — | |
| SCHEMBL12021588 | 0.57 | AKT1 (0.37) | ADORA2AADORA1 | |
| SCHEMBL23346951 | 0.56 | PIK3CB (0.42) | NOS3NOS2ADORA2AADORA2BADORA1 | |
| SCHEMBL3286320 | 0.55 | RXFP1 (0.41) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180107-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-09-16 | — | — | WO | disclosed |