Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | LTK | P29376 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.32 |
| ▸ | CDK7 | P50613 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866825 | 0.76 | CYP1A2 (0.35) | RPS6KA3CHEK1LRRK2 | |
| SCHEMBL23815859 | 0.70 | NOS3 (0.33) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20096935 | 0.69 | KDR (0.39) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL14933945 | 0.59 | — | — | |
| SCHEMBL13866826 | 0.55 | CYP1A2 (0.35) | RPS6KA3CHEK1LRRK2 | |
| SCHEMBL7519562 | 0.54 | — | — | |
| SCHEMBL1718947 | 0.52 | — | — | |
| SCHEMBL9413248 | 0.52 | RET (0.36) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL18520344 | 0.52 | RET (0.36) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL24954034 | 0.52 | KDR (0.40) | DAPK3PRKD3MAP4K4CSF1RRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180107-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-09-16 | — | — | WO | disclosed |