Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.62 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31562917 | 1.00 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23818012 | 0.89 | ALDH1A1 (0.81) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL25455158 | 0.87 | ALDH1A1 (0.78) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23817999 | 0.85 | ALDH1A1 (0.74) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23818011 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL25455169 | 0.78 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23818002 | 0.78 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23818000 | 0.78 | ALDH1A1 (0.72) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23818006 | 0.78 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23818001 | 0.77 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | ALDH1A1 4563/4885RAB9A 1865/4885NPC1 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.