Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 10/20 | 0.61 |
| ▸ | HSPA2 | P54652 | 4/20 | 0.61 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.59 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818759 | 0.83 | HSPA5 (0.63) | HSPA5HSPA2HSPA9HSPA1AAGTR2 | |
| SCHEMBL23818768 | 0.80 | HSPA5 (0.53) | HSPA5HSPA2HSPA9AGTR2CTSL | |
| SCHEMBL23818889 | 0.78 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1AAGTR2 | |
| SCHEMBL23804617 | 0.77 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1ACTSL | |
| SCHEMBL23804618 | 0.77 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1ACTSL | |
| SCHEMBL23818887 | 0.77 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1ATSHR | |
| SCHEMBL23804616 | 0.69 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1ATP53 | |
| SCHEMBL23804612 | 0.69 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1ATP53 | |
| SCHEMBL23804614 | 0.69 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1ATP53 | |
| SCHEMBL21241768 | 0.68 | SCD (0.60) | CTSLKMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183942-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-09-16 | — | — | WO | disclosed |