Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 6/20 | 0.72 |
| ▸ | HSPA2 | P54652 | 4/20 | 0.72 |
| ▸ | HSPA9 | P38646 | 4/20 | 0.72 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.72 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23804620 | 0.84 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA8DRD2 | |
| SCHEMBL23804624 | 0.84 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA8DRD2 | |
| SCHEMBL8558332 | 0.82 | HSPA5 (0.71) | HSPA5HSPA2HSPA9HSPA8NPC1 | |
| SCHEMBL29904457 | 0.82 | HSPA5 (0.71) | HSPA5HSPA2HSPA9HSPA8NPC1 | |
| SCHEMBL23818768 | 0.78 | HSPA5 (0.53) | HSPA5HSPA2HSPA9HSPA8TAS1R3 | |
| SCHEMBL23818761 | 0.77 | HSPA5 (0.68) | HSPA5HSPA2HSPA9HSPA8NPC1 | |
| SCHEMBL23804603 | 0.73 | HSPA5 (0.76) | HSPA5HSPA2HSPA9HSPA8NPC1 | |
| SCHEMBL23804600 | 0.73 | HSPA5 (0.76) | HSPA5HSPA2HSPA9HSPA8NPC1 | |
| SCHEMBL6885830 | 0.70 | HSPA5 (0.58) | HSPA5HSPA2HSPA9HSPA8DRD2 | |
| SCHEMBL13212233 | 0.69 | ALDH1A1 (0.66) | MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183942-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-09-16 | — | — | WO | disclosed |