Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.53 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23817969 | 0.91 | FNIP1 (0.67) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23818489 | 0.88 | FNIP1 (0.49) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25455177 | 0.81 | FNIP1 (0.53) | FNIP1FEM1BALDH1A1NOTUMMAPT | |
| SCHEMBL23817966 | 0.79 | FEM1B (0.61) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23817939 | 0.78 | FEM1B (0.52) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25455181 | 0.78 | FEM1B (0.47) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25171623 | 0.73 | FEM1B (0.68) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25386717 | 0.71 | NOTUM (0.58) | NOTUMKMT2APDE3BPDE3APOLB | |
| SCHEMBL30132890 | 0.71 | FEM1B (0.61) | FNIP1FEM1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10274847 | 0.71 | NOTUM (0.65) | ALDH1A1NOTUMMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |