Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.67 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818490 | 0.91 | FNIP1 (0.53) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25455177 | 0.90 | FNIP1 (0.53) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817966 | 0.88 | FEM1B (0.61) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23818481 | 0.84 | FEM1B (0.55) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817837 | 0.84 | FEM1B (0.54) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25171623 | 0.83 | FEM1B (0.68) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23804991 | 0.81 | FNIP1 (1.00) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23804989 | 0.80 | FEM1B (0.61) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30132890 | 0.80 | FEM1B (0.61) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23818422 | 0.79 | FEM1B (0.60) | FNIP1FEM1BALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | FNIP1 3/4885FEM1B 1/4885ALDH1A1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.