SCHEMBL23818912

SCHEMBL23818912

COCCOP(=O)(N[C@@H](C)C(=O)OC(C)C)OCC(C#N)(OC)[C@@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)c1ccc2c(N)ncnn12

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BTN3A1 O00481 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23819014 0.94 — —
SCHEMBL23819100 0.94 — —
SCHEMBL26335968 0.89 BTN3A1 (0.31) BTN3A1
SCHEMBL23819243 0.89 BTN3A1 (0.31) BTN3A1
SCHEMBL23819050 0.87 RIPK1 (0.32) BTN3A1
SCHEMBL23819313 0.87 BTN3A1 (0.34) BTN3A1
SCHEMBL26333931 0.87 RIPK1 (0.32) —
SCHEMBL23819085 0.86 BTN3A1 (0.33) BTN3A1
SCHEMBL23819167 0.86 RIPK1 (0.31) —
SCHEMBL26333779 0.86 RIPK1 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210284670-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2021-09-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284670-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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