Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.31 |
| ▸ | AXL | P30530 | 2/20 | 0.30 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26295855 | 0.95 | POLRMT (0.33) | POLRMT | |
| SCHEMBL23818650 | 0.94 | POLRMT (0.35) | POLRMTRIPK1AXL | |
| SCHEMBL23818943 | 0.94 | POLRMT (0.35) | POLRMTRIPK1AXL | |
| SCHEMBL23818539 | 0.92 | POLRMT (0.34) | POLRMT | |
| SCHEMBL23819157 | 0.92 | POLRMT (0.34) | POLRMTAXL | |
| SCHEMBL23818850 | 0.92 | POLRMT (0.34) | POLRMT | |
| SCHEMBL23819071 | 0.90 | BTN3A1 (0.38) | POLRMTRIPK1 | |
| SCHEMBL23818695 | 0.88 | TMPRSS2 (0.34) | TMPRSS2 | |
| SCHEMBL23819232 | 0.87 | POLRMT (0.33) | POLRMTRIPK1 | |
| SCHEMBL23818530 | 0.87 | POLRMT (0.31) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284670-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284670-A1 | ANTIVIRAL COMPOUNDS | MAVS, HAVCR2, ZC3HAV1 | POLRMT 535/4885RIPK1 666/4885AXL 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.