Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 16/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882184 | 0.91 | RIPK1 (0.68) | RIPK1MAOBMEP1BCES2CES1 | |
| SCHEMBL23803566 | 0.86 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL17874145 | 0.81 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL23803521 | 0.79 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL23803517 | 0.78 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL17882167 | 0.76 | RIPK1 (0.70) | RIPK1MAOBMEP1B | |
| SCHEMBL23803571 | 0.75 | RIPK1 (0.50) | RIPK1MAOB | |
| SCHEMBL23803531 | 0.75 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL17882281 | 0.72 | RIPK1 (0.65) | RIPK1MAOB | |
| SCHEMBL17882185 | 0.72 | RIPK1 (0.71) | RIPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883918-B1 | RIP1 INHIBITORS | SIRONAX LTD (KY) | 2023-07-19 | — | — | EP | disclosed |
| US-20210284598-A1 | RIP1 Inhibitors | SIRONAX LTD (KY) | 2021-09-16 | — | — | US | disclosed |
| CN-113272272-A | RIP1 inhibitors | 圣瑞诺有限公司 | 2021-08-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284598-A1 | RIP1 Inhibitors | RIPK1, RIPK3, RIPK4 | RIPK1 1/4885MAOB 4796/4885MEP1B 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.