Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381196 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL12246287 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL6295802 | 0.80 | ATM (0.68) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL7806984 | 0.80 | ATM (0.68) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL12246309 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNARAB9ACYP2C9CYP2C19 | |
| SCHEMBL2381923 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNARAB9ACYP2C9CYP2C19 | |
| SCHEMBL9301046 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL23766670 | 0.77 | ATM (0.65) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL1793176 | 0.77 | GAA (0.76) | ALDH1A1LMNAGLAATMGAA | |
| SCHEMBL31206887 | 0.77 | GAA (0.76) | ALDH1A1LMNAGLAATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017776-B2 | Methods for synthesis of acyloxyalkyl compounds | XENOPORT, INC. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100041882-A1 | METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-7662987-B2 | Oxidation of 1-acyl alkyl compound under anhydrous condition | XENOPORT, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-20050070715-A1 | Methods for synthesis of acyloxyalkyl compounds | ARBOR PHARMACEUTICALS, LLC | 2005-03-31 | — | — | US | disclosed |
| WO-2005010011-A2 | METHODS OF SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070715-A1 | Methods for synthesis of acyloxyalkyl compounds | AADAC, CYP2D6, CYP3A7 | ALDH1A1 103/4885LMNA 3411/4885GLA 866/4885 |
| US-20100041882-A1 | METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | AADAC, CYP2D6, CYP3A7 | ALDH1A1 103/4885LMNA 3411/4885GLA 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.