SCHEMBL27329595

SCHEMBL27329595

CP(=O)(O)CN1CCN(CC(N)=O)CCN(CP(C)(=O)O)CCN(CP(C)(=O)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
POLB P06746 2/20 0.38
PKM P14618 2/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.36
RAD52 P43351 1/20 0.33
SLC2A1 P11166 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19860510 0.84 KDM4E (0.50) KDM4EPOLBPKMTSHRALDH1A1
SCHEMBL31222574 0.83 MAPT (0.48) KDM4EPOLBPKMTSHRALDH1A1
SCHEMBL16645399 0.82 HSD17B10 (0.44) KDM4EPOLBTSHRALDH1A1MAPT
SCHEMBL13992938 0.82 HSD17B10 (0.44) KDM4EPOLBTSHRALDH1A1MAPT
SCHEMBL2821117 0.78 KDM4E (0.68) KDM4EPOLBPKMTSHRALDH1A1
SCHEMBL3624681 0.78 KDM4E (0.68) KDM4EPOLBPKMTSHRALDH1A1
SCHEMBL458012 0.78 KDM4E (0.68) KDM4EPOLBPKMTSHRALDH1A1
SCHEMBL5307853 0.78
SCHEMBL18537936 0.78 HSD17B10 (0.40) KDM4EPOLBTSHRALDH1A1MAPT
SCHEMBL23822802 0.78 KDM4E (0.44) KDM4EPOLBTSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
WO-2024129600-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-06-20 WO disclosed
WO-2024112612-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-05-30 WO disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R KDM4E 3543/4885POLB 4538/4885PKM 2922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.