Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.30 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234622 | 0.84 | SIGMAR1 (0.32) | SIGMAR1MEN1KMT2ATSHRL3MBTL3 | |
| SCHEMBL23784287 | 0.84 | L3MBTL3 (0.42) | SIGMAR1MEN1KMT2ATSHRTP53 | |
| SCHEMBL24179813 | 0.84 | SIGMAR1 (0.35) | SIGMAR1MEN1KMT2ATSHRTP53 | |
| SCHEMBL10284012 | 0.83 | SIGMAR1 (0.41) | SIGMAR1MEN1KMT2ATSHRTP53 | |
| SCHEMBL23219677 | 0.82 | SMN1; SMN2 (0.33) | MEN1KMT2A | |
| SCHEMBL22098593 | 0.81 | HRH3 (0.32) | — | |
| SCHEMBL10236308 | 0.81 | MEN1 (0.43) | SIGMAR1MEN1KMT2ADRD2DRD3 | |
| SCHEMBL7699144 | 0.80 | HRH3 (0.33) | L3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL21038317 | 0.80 | TSHR (0.35) | SIGMAR1MEN1KMT2ADRD2DRD3 | |
| SCHEMBL13860756 | 0.78 | L3MBTL3 (0.33) | L3MBTL3MBTD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180235-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | 四川海思科制药有限公司 | 2021-09-16 | — | — | WO | disclosed |