Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24777034 | 0.61 | IDO1 (0.46) | — | |
| SCHEMBL12731429 | 0.60 | TSHR (0.38) | — | |
| SCHEMBL24876403 | 0.58 | IDO1 (0.42) | — | |
| SCHEMBL23823302 | 0.57 | — | — | |
| SCHEMBL5415177 | 0.56 | HTT (0.42) | HTTPTK2 | |
| SCHEMBL2267087 | 0.56 | MAPT (0.46) | HTTPTK2 | |
| SCHEMBL21195832 | 0.55 | HTT (0.37) | HTTPTK2 | |
| SCHEMBL16276755 | 0.55 | HTT (0.40) | HTTPTK2 | |
| SCHEMBL25193094 | 0.55 | NOS1 (0.38) | HTTPTK2 | |
| SCHEMBL24495528 | 0.54 | NOS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180235-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | 四川海思科制药有限公司 | 2021-09-16 | — | — | WO | disclosed |