SCHEMBL23823786

SCHEMBL23823786

c1ccc(-c2ccc3sc4cccc(-c5ccc(-c6cccc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)c6)c6c5oc5ccccc56)c4c3c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 2/20 0.35
PIM1 P11309 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
BRDT Q58F21 1/20 0.35
ALOX5 P09917 2/20 0.34
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.33
MAPT P10636 4/20 0.32
ALDH1A1 P00352 3/20 0.31
TSHR P16473 2/20 0.31
POLB P06746 2/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25458069 0.94 ALOX5 (0.37) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL22376985 0.94 BRDT (0.38) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL22376010 0.94 BRDT (0.38) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL25459075 0.93 BRDT (0.37) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL25458075 0.92 BRDT (0.35) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL25458076 0.92 ALOX5 (0.38) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL22376801 0.91 BRDT (0.38) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL19802683 0.91 PLA2G2A (0.34) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL19802130 0.91 PLA2G2A (0.34) PIM3PIM1CSNK2A2CSNK2BPIM2
SCHEMBL26723346 0.91 PLA2G2A (0.34) PIM3PIM1CSNK2A2CSNK2BPIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157151-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230157151-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
WO-2021180625-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2021-09-16 WO disclosed