Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701847 | 0.89 | CA2 (0.47) | CA2ALDH1A1HCAR2KEAP1NFE2L2 | |
| SCHEMBL18356862 | 0.89 | CA2 (0.47) | CA2ALDH1A1HCAR2KEAP1NFE2L2 | |
| SCHEMBL17048416 | 0.89 | CA2 (0.47) | CA2ALDH1A1HCAR2KEAP1NFE2L2 | |
| SCHEMBL16994444 | 0.89 | CA2 (0.47) | CA2ALDH1A1HCAR2KEAP1NFE2L2 | |
| SCHEMBL15701848 | 0.83 | CA2 (0.51) | CA2ALDH1A1HCAR2HTR7TMEM97 | |
| SCHEMBL10032797 | 0.82 | CA2 (0.54) | CA2ALDH1A1HTR7TMEM97SIGMAR1 | |
| SCHEMBL10032800 | 0.78 | CA2 (0.53) | CA2ALDH1A1HTR7TMEM97SIGMAR1 | |
| SCHEMBL15689786 | 0.78 | CA2 (0.47) | CA2ALDH1A1HCAR2HTR7TMEM97 | |
| SCHEMBL13063460 | 0.77 | CA2 (0.51) | CA2ALDH1A1HTR7TMEM97SIGMAR1 | |
| SCHEMBL10032813 | 0.77 | CA2 (0.46) | CA2ALDH1A1HTR7TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021179049-A1 | TREATMENT OF DISORDERS ASSOCIATED WITH OXIDATIVE STRESS AND COMPOUNDS FOR SAME | THE UNIVERSITY OF ADELAIDE (AU) | 2021-09-16 | — | — | WO | disclosed |