Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69295 | 0.86 | NPSR1 (0.48) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL23824150 | 0.83 | NPSR1 (0.45) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL9799881 | 0.82 | ALDH1A1 (0.34) | KDM4ETSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL546639 | 0.77 | NPSR1 (0.46) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL19763311 | 0.75 | KDM4C (0.48) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL5761874 | 0.75 | NPSR1 (0.48) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL19207970 | 0.73 | NPSR1 (0.46) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL20168105 | 0.73 | NNMT (0.41) | KDM4EALDH1A1NNMTGLAGAA | |
| SCHEMBL19780563 | 0.73 | NPSR1 (0.46) | KDM4ESTAT3HIF1ANPSR1KDM4C | |
| SCHEMBL13726965 | 0.73 | NPSR1 (0.46) | KDM4ESTAT3HIF1ANPSR1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021181122-A1 | GPR52 MODULATOR COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2021-09-16 | — | — | WO | disclosed |