Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 5/20 | 0.39 |
| ▸ | PDE6A | P16499 | 5/20 | 0.39 |
| ▸ | PDE6G | P18545 | 5/20 | 0.39 |
| ▸ | PDE6B | P35913 | 5/20 | 0.39 |
| ▸ | PDE6C | P51160 | 5/20 | 0.39 |
| ▸ | PDE6H | Q13956 | 5/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830332 | 0.91 | HSD17B10 (0.40) | HSD17B10PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL23830420 | 0.90 | HSD17B10 (0.39) | HSD17B10PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL23830414 | 0.89 | PDE6D (0.41) | HSD17B10PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL23830385 | 0.82 | PDE6D (0.52) | HSD17B10PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL23830398 | 0.81 | PDE6D (0.41) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830389 | 0.80 | PDE6D (0.42) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830392 | 0.80 | PDE6D (0.40) | HSD17B10PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL23830386 | 0.76 | RORC (0.34) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830352 | 0.75 | PDE6D (0.44) | HSD17B10PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL23830291 | 0.70 | HSD17B10 (0.56) | HSD17B10KDM5BMAPTNPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | CADILA HEALTHCARE LIMITED (IN) | 2021-09-23 | — | — | US | disclosed |
| CN-112543757-A | Condensed azaheteroaryl compounds having antibacterial activity against tubercle bacillus | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | DPEP1, SAT1, PEPD | HSD17B10 1210/4885PDE6D 3804/4885PDE6A 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.