Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645249 | 0.92 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL16920141 | 0.89 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL17781100 | 0.89 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL25338637 | 0.87 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL26767956 | 0.82 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL31347036 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL24496548 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL3968921 | 0.80 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL16522671 | 0.80 | KMT2A (0.47) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL1621780 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | CADILA HEALTHCARE LIMITED (IN) | 2021-09-23 | — | — | US | disclosed |
| CN-112543757-A | Condensed azaheteroaryl compounds having antibacterial activity against tubercle bacillus | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | DPEP1, SAT1, PEPD | ALDH1A1 152/4885SMN1; SMN2 4576/4885MAPT 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.