Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 2/20 | 0.38 |
| ▸ | PDE6A | P16499 | 2/20 | 0.38 |
| ▸ | PDE6G | P18545 | 2/20 | 0.38 |
| ▸ | PDE6B | P35913 | 2/20 | 0.38 |
| ▸ | PDE6C | P51160 | 2/20 | 0.38 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830352 | 0.88 | PDE6D (0.44) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830385 | 0.87 | PDE6D (0.52) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830317 | 0.87 | PDE6D (0.37) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830296 | 0.86 | PDE6D (0.37) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830376 | 0.84 | PDE6D (0.45) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830357 | 0.82 | PDE6D (0.40) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830339 | 0.81 | ALOX15 (0.41) | MAPTMAPK1ALDH1A1TP53HSD17B10 | |
| SCHEMBL23830370 | 0.78 | PDE6D (0.44) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830276 | 0.75 | PDE6D (0.54) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830408 | 0.74 | PDE6D (0.38) | PDE6DPDE6APDE6GPDE6BPDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | CADILA HEALTHCARE LIMITED (IN) | 2021-09-23 | — | — | US | disclosed |
| CN-112543757-A | Condensed azaheteroaryl compounds having antibacterial activity against tubercle bacillus | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | DPEP1, SAT1, PEPD | PDE6D 3804/4885PDE6A 1704/4885PDE6G 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.