SCHEMBL23830581

SCHEMBL23830581

C[C@H]1CN(c2ncccn2)CCN1C(=O)N1N=CC[C@H]1c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 17/20 0.60
SLC6A7 Q99884 2/20 0.48
GRM1 Q13255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23830578 1.00 RIPK1 (0.60) RIPK1SLC6A7GRM1
SCHEMBL23842645 1.00 RIPK1 (0.60) RIPK1SLC6A7GRM1
SCHEMBL23830582 1.00 RIPK1 (0.60) RIPK1SLC6A7GRM1
SCHEMBL23842698 0.90 RIPK1 (0.51) RIPK1
SCHEMBL23830730 0.90 RIPK1 (0.51) RIPK1
SCHEMBL23830707 0.90 RIPK1 (0.51) RIPK1
SCHEMBL23830709 0.90 RIPK1 (0.51) RIPK1
SCHEMBL23830926 0.90 RIPK1 (0.51) RIPK1SLC6A7
SCHEMBL23830732 0.90 RIPK1 (0.51) RIPK1
SCHEMBL23830923 0.90 RIPK1 (0.51) RIPK1SLC6A7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883925-A1 CYCLIC UREAS Sironax Ltd (KY) 2021-09-29 EP disclosed
US-20210292305-A1 Cyclic Ureas SIRONAX LTD (KY) 2021-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292305-A1 Cyclic Ureas RIPK1, RIPK3, RIPK4 RIPK1 1/4885SLC6A7 4405/4885GRM1 1483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.