Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693960 | 0.86 | ESR2 (0.49) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL28687778 | 0.86 | ESR2 (0.49) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL29161083 | 0.84 | ESR2 (0.44) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL1488405 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2HDAC1ESR2NR1H2 | |
| SCHEMBL26079206 | 0.82 | HPGD (0.44) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL513246 | 0.82 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL21588714 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2HDAC1ESR2NR1H2 | |
| SCHEMBL25179490 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2HDAC1ESR2NR1H2 | |
| SCHEMBL26079201 | 0.80 | USP2 (0.56) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL14880125 | 0.80 | USP2 (0.43) | USP2SMN1; SMN2HDAC1ESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | USP2 62/4885SMN1; SMN2 1927/4885HDAC1 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.