SCHEMBL23830891

SCHEMBL23830891

O=C(N1CCN(c2ncc(F)cn2)CC1)N1N=CCC1c1cc(F)cc(F)c1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 17/20 0.54
SLC6A9 P48067 1/20 0.38
PARP1 P09874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23831062 0.89 RIPK1 (0.55) RIPK1PARP1
SCHEMBL23831058 0.89 RIPK1 (0.55) RIPK1PARP1
SCHEMBL23830871 0.89 RIPK1 (0.56) RIPK1SLC6A9
SCHEMBL23831043 0.87 RIPK1 (0.59) RIPK1
SCHEMBL24055487 0.85 RIPK1 (0.50) RIPK1
SCHEMBL30173597 0.85 RIPK1 (0.50) RIPK1
SCHEMBL25278541 0.85 RIPK1 (0.50) RIPK1
SCHEMBL24055256 0.85 RIPK1 (0.47) RIPK1PARP1
SCHEMBL28949325 0.85 RIPK1 (0.47) RIPK1
SCHEMBL23842597 0.84 RIPK1 (0.62) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210292305-A1 Cyclic Ureas SIRONAX LTD (KY) 2021-09-23 US disclosed
US-20210292305-A1 Cyclic Ureas SIRONAX LTD (KY) 2021-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292305-A1 Cyclic Ureas RIPK1, RIPK3, RIPK4 RIPK1 1/4885SLC6A9 4181/4885PARP1 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.