Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 17/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831022 | 0.97 | RIPK1 (0.65) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23830668 | 0.96 | RIPK1 (0.66) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23830662 | 0.89 | RIPK1 (0.56) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23842694 | 0.85 | POLB (0.57) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23830698 | 0.85 | POLB (0.54) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23830509 | 0.82 | RIPK1 (0.63) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23808092 | 0.80 | RIPK1 (0.65) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23830571 | 0.80 | RIPK1 (0.59) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL23808090 | 0.80 | RIPK1 (0.68) | RIPK1POLBNPC1RAB9AMAPT | |
| SCHEMBL5527901 | 0.79 | POLB (0.82) | RIPK1POLBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | RIPK1 1/4885POLB 4003/4885NPC1 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.