SCHEMBL30104879

SCHEMBL30104879

O=C(Nc1cc(Cl)nc(Cl)c1)Nc1ccccc1CO

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 3/20 0.60
TRPV1 Q8NER1 3/20 0.58
IGF1R P08069 1/20 0.50
POLB P06746 3/20 0.48
NHERF1 O14745 1/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 3/20 0.46
HTT P42858 2/20 0.46
DHODH Q02127 1/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
CASP3 P42574 2/20 0.45
SENP7 Q9BQF6 2/20 0.45
LMNA P02545 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP6 Q9GZR1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23831653 1.00 S1PR2 (0.60) S1PR2TRPV1IGF1RPOLBNHERF1
SCHEMBL23831645 0.89 TRPV1 (0.60) S1PR2TRPV1IGF1RPOLBMEN1
SCHEMBL30104873 0.89 TRPV1 (0.60) S1PR2TRPV1IGF1RPOLBMEN1
SCHEMBL30105332 0.85 DHODH (0.62) TRPV1NHERF1MEN1KMT2AMAPT
SCHEMBL23831572 0.85 DHODH (0.62) TRPV1NHERF1MEN1KMT2AMAPT
SCHEMBL23831748 0.85 SMARCA2 (0.60) TRPV1POLBMEN1KMT2AMAPT
SCHEMBL23831562 0.84 S1PR2 (0.58) S1PR2TRPV1IGF1RMEN1KMT2A
SCHEMBL23831950 0.83 TRPV1 (0.55) TRPV1POLBMEN1KMT2AMAPT
SCHEMBL23831598 0.82 S1PR2 (0.55) S1PR2TRPV1IGF1RMEN1KMT2A
SCHEMBL30104971 0.82 S1PR2 (0.55) S1PR2TRPV1IGF1RMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121415-A1 INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES Univerzita Palackého v Olomouci (CZ) 2023-01-25 EP claimed