Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MECP2 | P51608 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105050 | 1.00 | RAB9A (0.50) | RAB9AALDH1A1HTTCNR1KCNK3 | |
| SCHEMBL23832066 | 0.87 | AR (0.45) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL27077630 | 0.87 | CNR1 (0.53) | RAB9AALDH1A1CNR1KCNK3KCNK9 | |
| SCHEMBL30105096 | 0.87 | CNR1 (0.43) | RAB9AALDH1A1HTTCNR1KCNK3 | |
| SCHEMBL23831972 | 0.87 | CNR1 (0.43) | RAB9AALDH1A1HTTCNR1KCNK3 | |
| SCHEMBL23831797 | 0.87 | CNR1 (0.47) | RAB9AALDH1A1HTTCNR1KCNK3 | |
| SCHEMBL30792378 | 0.83 | RAB9A (0.42) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL23831606 | 0.83 | SMARCA2 (0.54) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL23831824 | 0.83 | RAB9A (0.42) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL23831642 | 0.81 | TRPV1 (0.49) | RAB9AALDH1A1HTTCNR1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021185391-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-09-23 | — | — | WO | disclosed |