Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23848610 | 0.89 | KMT2A (0.50) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL23832805 | 0.89 | KMT2A (0.45) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL25168299 | 0.89 | FKBP1A (0.43) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL23832785 | 0.88 | KMT2A (0.42) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL23848476 | 0.84 | KMT2A (0.45) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL25501797 | 0.84 | KMT2A (0.44) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL25501803 | 0.83 | MAPT (0.41) | POLBKMT2AMGAT2MOGAT2MAPT | |
| SCHEMBL25502088 | 0.83 | KMT2A (0.40) | FKBP1AKMT2AGLAMGAT2MOGAT2 | |
| SCHEMBL25502166 | 0.83 | FKBP1A (0.42) | POLBFKBP1AKMT2AGLAMGAT2 | |
| SCHEMBL23848606 | 0.82 | KMT2A (0.43) | POLBFKBP1AKMT2AGLAMGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382270-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC (US) | 2025-12-18 | — | — | US | disclosed |
| US-12398103-B2 | 3-diarylmethylenes and uses thereof | ATUX ISKAY LLC (US) | 2025-08-26 | — | — | US | disclosed |
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC | 2023-05-11 | — | — | US | disclosed |
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC | 2023-05-11 | — | — | US | disclosed |
| EP-4121031-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | Atux Iskay LLC (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188949-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC (US) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382270-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | MYC, MYCBP, FOXO1 | POLB 1988/4885FKBP1A 1315/4885KMT2A 742/4885 |
| US-12398103-B2 | 3-diarylmethylenes and uses thereof | MYC, MYCBP, FOXO1 | POLB 1988/4885FKBP1A 1315/4885KMT2A 742/4885 |
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | MYC, MYCBP, FOXO1 | POLB 1988/4885FKBP1A 1315/4885KMT2A 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.