Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL27206170 | 1.00 | SLC7A5 (0.58) | SLC7A5TSHRALDH1A1GRIK1GRIK2 | |
| Valine SCHEMBL4045692 | 0.90 | SLC7A5 (0.71) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Dodecane SCHEMBL28109673 | 0.88 | SLC7A5 (0.68) | SLC7A5TSHRALDH1A1GRIK1GRIK2 | |
| Valine SCHEMBL11005807 | 0.88 | SLC7A5 (0.68) | SLC7A5TSHRALDH1A1GRIK1GRIK2 | |
| Threonine SCHEMBL28254028 | 0.87 | ALDH1A1 (0.43) | SLC7A5TSHRALDH1A1GRIK1GRIK2 | |
| Alanine SCHEMBL28014257 | 0.86 | TSHR (0.50) | TSHRALDH1A1GRIK1GRIK2SLC1A2 | |
| Isoleucine SCHEMBL28819073 | 0.85 | ALDH1A1 (0.41) | SLC7A5TSHRALDH1A1GRIK1GRIK2 | |
| Alanine SCHEMBL28481821 | 0.84 | TSHR (0.48) | TSHRALDH1A1GRIK1GRIK2SLC1A2 | |
| Valine SCHEMBL28133161 | 0.83 | SLC7A5 (0.75) | SLC7A5SLC1A2SLC1A1DPP4SLC1A3 | |
| Valine SCHEMBL28133160 | 0.83 | SLC7A5 (0.75) | SLC7A5SLC1A2SLC1A1DPP4SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547653-B1 | N-CARBOMETHOXY-N-METHOXY-(2-CHLOROMETHYL)-ANILINES, THEIR PREPARATION AND THEIR USE AS PRECURSORS FOR PREPARING 2-(PYRAZOL-3'-YLOXYMETHYLENE)-ANILIDES | BASF SE (DE) | 2015-01-28 | — | — | EP | claimed |
| CN-102858735-B | N-carbomethoxy-n-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides | BASF SE | 2014-12-10 | — | — | CN | claimed |
| EP-2547653-A1 | N-CARBOMETHOXY-N-METHOXY-(2-CHLOROMETHYL)-ANILINES, THEIR PREPARATION AND THEIR USE AS PRECURSORS FOR PREPARING 2-(PYRAZOL-3'-YLOXYMETHYLENE)-ANILIDES | BASF SE (DE) | 2013-01-23 | — | — | EP | claimed |
| CN-102858735-A | N-carbomethoxy-n-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides | BASF SE | 2013-01-02 | — | — | CN | claimed |
| WO-2011113884-A1 | N-CARBOMETHOXY-N-METHOXY-(2-CHLOROMETHYL)-ANILINES, THEIR PREPARATION AND THEIR USE AS PRECURSORS FOR PREPARING 2-(PYRAZOL-3'-YLOXYMETHYLENE)-ANILIDES | BASF SE (DE) | 2011-09-22 | — | — | WO | claimed |
| EP-4247800-A1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-09-27 | — | — | EP | disclosed |
| US-20230286930-A1 | N -SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-09-14 | — | — | US | disclosed |
| CN-111620896-B | Preparation method of tetra-coordinated N, N-chelated diaryl borate compound with 8-aminoquinoline derivative as bidentate ligand | 石河子大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111620896-B | Preparation method of tetra-coordinated N, N-chelated diaryl borate compound with 8-aminoquinoline derivative as bidentate ligand | 石河子大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115210218-A | Pesticidally active cyclic amine compounds | 先正达农作物保护股份公司 | 2022-10-18 | — | — | CN | disclosed |
| WO-2022106589-A1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-05-27 | — | — | WO | disclosed |
| CN-111620896-A | Preparation method of tetra-coordinated N, N-chelated diaryl borate compound with 8-aminoquinoline derivative as bidentate ligand | 石河子大学 | 2020-09-04 | — | — | CN | disclosed |
| US-6329530-B1 | REACTING ALKYL VINYL ETHER WITH PHOSGENE OR PHOSGENE DERIVATIVE TO FORM ACYL CHLORIDE DERIVATIVE; DEHYDROCHLORIANTING TO FORM 3-ALKOXYACRYLOYL CHLORIDE COMPOUND; REACTING WITH ALKYLHYDRAZINE | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-11 | — | — | US | disclosed |
| EP-0769512-B1 | Process for preparing polycondensation polymers using haloiminium salts as condensation agents | MITSUI CHEMICALS INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| CN-1220667-A | Morphinane derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |
| EP-0769512-A2 | Process for preparing polycondensation polymers | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0213450-B1 | Aminoacyl derivatives of 4,9-dihydro-10H-pyrido[3,2-b]-thieno-[3,2-e][1,4]diazepinone and of 4,9-dihydro-10H-pyrido[3,2-b]-thieno[3,4-e][1,4]diazepinone, their preparation and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1992-01-08 | — | — | EP | disclosed |
| CN-87105898-A | N-(sProcess and intermediates for the preparation of -3-alkylheptanoyl -D-r-glutamyl -glycyl -D-alanyl | — | 1988-03-09 | — | — | CN | disclosed |
| US-4659707-A | ANTIULCER, ANTISECRETORY, ANTIMUSCARINIC AND/OR ANTISPASMODIC AGENTS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1987-04-21 | — | — | US | disclosed |
| EP-0213450-A2 | Aminoacyl derivatives of 4,9-dihydro-10H-pyrido[3,2-b]-thieno-[3,2-e][1,4]diazepinone and of 4,9-dihydro-10H-pyrido[3,2-b]-thieno[3,4-e][1,4]diazepinone, their preparation and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1987-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286930-A1 | N -SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, CYP2E1, CYP7A1 | SLC7A5 2183/4885TSHR 1534/4885ALDH1A1 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.