Alanine

Alanine

SCHEMBL28014257

CC(N)C(=O)O.CCCCCCl

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 2/20 0.44
SLC1A2 P43004 2/20 0.44
SLC1A1 P43005 2/20 0.44
ACE2 Q9BYF1 1/20 0.42
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SLC1A3 P43003 1/20 0.41
MAPT P10636 1/20 0.41
TP53 P04637 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
FAAH O00519 1/20 0.40
SLC15A1 P46059 1/20 0.40
OPRM1 P35372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanine SCHEMBL28481821 0.98 TSHR (0.48) TSHRALDH1A1GRIK1GRIK2SLC1A2
Alanine SCHEMBL27852198 0.93 TSHR (0.50) TSHRALDH1A1GRIK1GRIK2SLC1A2
SCHEMBL28232551 0.86 TSHR (0.55) TSHRALDH1A1ACE2GPR84FFAR1
Decane SCHEMBL30872389 0.86 GPR84 (0.54) TSHRALDH1A1GRIK1GRIK2SLC1A2
Dodecane SCHEMBL27537310 0.86 GPR84 (0.54) TSHRALDH1A1GRIK1GRIK2SLC1A2
Alanine SCHEMBL27755627 0.86 SLC7A5 (0.42) GRIK1GRIK2SLC1A2SLC1A1TDP1
Valine SCHEMBL27206170 0.86 SLC7A5 (0.58) TSHRALDH1A1GRIK1GRIK2SLC1A2
Valine SCHEMBL2383315 0.86 SLC7A5 (0.58) TSHRALDH1A1GRIK1GRIK2SLC1A2
SCHEMBL27947850 0.85 TSHR (0.54) TSHRALDH1A1GRIK1GRIK2SLC1A2
Lactic Acid SCHEMBL28942349 0.84 TSHR (0.52) TSHRALDH1A1ACE2GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104607163-B A kind of micro- chiral adjusting cellulose chromatography stationary phase, preparation method and applications 北京迪马欧泰科技发展中心 2018-05-15 CN disclosed
CN-104607163-A Micro-chiral adjusting cellulose chromatography stationary phase, as well as preparation method and application thereof BEIJING SCIENCE & TECH 2015-05-13 CN disclosed