SCHEMBL238332

SCHEMBL238332

O=C(Oc1ccc(-c2cccc3ccccc23)cc1)Oc1ccc(-c2cccc3ccccc23)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.60
PPARA Q07869 13/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2C19 P33261 2/20 0.60
PPARD Q03181 1/20 0.60
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
MCL1 Q07820 1/20 0.49
ACMSD Q8TDX5 1/20 0.49
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
CYP1A2 P05177 1/20 0.48
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA7 P36544 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29672358 1.00 PPARG (0.60) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL238321 0.98 PPARG (0.58) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL246024 0.97 PPARG (0.61) PPARGPPARACYP2C9CYP2C19PPARD
Bicarbonate SCHEMBL28016107 0.95 PPARG (0.59) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL17942333 0.88 PPARG (0.62) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL30356799 0.88 PPARG (0.62) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL238319 0.85 HDAC8 (0.54) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL5706132 0.84 SLC6A3 (0.50) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL8210728 0.84 PPARG (0.58) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL2111830 0.84 PPARG (0.55) PPARGPPARACYP2C9CYP2C19PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
WO-2025228904-A1 LAYER STRUCTURE WITH AT LEAST TWO LAYERS HAVING DIFFERENT ENGRAVINGS COVESTRO DEUTSCHLAND AG (DE) 2025-11-06 WO disclosed
EP-4644131-A1 LAYER STRUCTURE COMPRISING AT LEAST TWO LAYERS HAVING DIFFERENT ENGRAVINGS Covestro Deutschland AG (DE) 2025-11-05 EP disclosed
US-12365775-B2 Process for partial colouring of plastic parts using solid colourants in colour- carrier layers COVESTRO DEUTSCHLAND AG (DE) 2025-07-22 US disclosed
US-20250205963-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-06-26 US disclosed
EP-4549163-A2 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2025-05-07 EP disclosed
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20250091332-A1 FILM STRUCTURE SUITABLE FOR RAPID LAMINATION COVESTRO DEUTSCHLAND AG (DE) 2025-03-20 US disclosed
EP-3055344-B1 POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP disclosed
EP-1742983-B1 PROCESS FOR PRODUCING POLYCARBONATE BAYER MATERIALSCIENCE AG (DE) 2008-02-27 EP disclosed
US-7279544-B2 Transesterification process for the production of polycarbonates having a low content of volatile compounds BAYER MATERIALSCIENCE AG (DE) 2007-10-09 US disclosed
US-7250483-B2 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2007-07-31 US disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 US disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 US disclosed
EP-1612231-A1 Inhibition of catalyst-active impurities in polycarbonate transesterification process Bayer MaterialScience AG (DE) 2006-01-04 EP disclosed
US-20050288407-A1 Thermally stabilized polycarbonate composition BAYER MATERIALSCIENCE AG 2005-12-29 US disclosed
EP-1609818-A2 Heat stabilised polycarbonate compositions Bayer MaterialScience AG (DE) 2005-12-28 EP disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed
US-20050131197-A1 Transesterification process for the production of polycarbonates having a low content of volatile compounds COVESTRO DEUTSCHLAND AG (DE) 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL PPARG 1607/4885PPARA 2258/4885CYP2C9 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.