Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 5/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15175066 | 0.81 | RAPGEF3 (0.78) | RAPGEF3ALBRAPGEF4 | |
| SCHEMBL15175065 | 0.81 | RAPGEF3 (0.78) | RAPGEF3ALBRAPGEF4 | |
| SCHEMBL20523698 | 0.80 | RAPGEF3 (0.77) | RAPGEF3 | |
| SCHEMBL20523773 | 0.76 | MAPT (0.52) | RAPGEF3ALBRAPGEF4 | |
| SCHEMBL22340285 | 0.72 | RAPGEF3 (0.47) | RAPGEF3ALBRAPGEF4 | |
| SCHEMBL15173845 | 0.72 | RAPGEF3 (0.76) | RAPGEF3ALBRAPGEF4 | |
| SCHEMBL15173844 | 0.72 | RAPGEF3 (0.76) | RAPGEF3ALBRAPGEF4 | |
| SCHEMBL922712 | 0.72 | MAPT (0.81) | RAPGEF3RAPGEF4 | |
| SCHEMBL922713 | 0.72 | MAPT (0.81) | RAPGEF3RAPGEF4 | |
| SCHEMBL15175655 | 0.71 | RAPGEF3 (0.76) | RAPGEF3ALBRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124489-B2 | EPAC antagonists | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124489-B2 | EPAC antagonists | EPAS1, GPR139, CRACR2A | RAPGEF3 5/4885ALB 4570/4885RAPGEF4 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.