Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18712169 | 0.80 | DPP7 (0.45) | DPP7TDP1RRM1S1PR1S1PR3 | |
| SCHEMBL13968330 | 0.80 | SLC1A2 (0.47) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL18712170 | 0.76 | ALDH1A1 (0.47) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL23836662 | 0.76 | ALDH1A1 (0.47) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL27637992 | 0.75 | DPP7 (0.66) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29472047 | 0.75 | DPP7 (0.66) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL23974045 | 0.74 | GRIK1 (0.50) | MAPTSLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL25006937 | 0.73 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL17941558 | 0.71 | DPP7 (0.50) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL17941556 | 0.71 | DPP7 (0.50) | DPP7ALDH1A1LMNAMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124525-B2 | Heteroaryl compounds useful as MK2 inhibitors | CELGENE CAR LLC (BM) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124525-B2 | Heteroaryl compounds useful as MK2 inhibitors | MKNK2, MKRN3, MKNK1 | DPP7 1580/4885ALDH1A1 4142/4885LMNA 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.