Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076107 | 0.87 | KCNH2 (0.73) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19924250 | 0.87 | KCNH2 (0.73) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19924248 | 0.87 | KCNH2 (0.73) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19924271 | 0.83 | TLR8 (0.72) | KCNH2TLR8TLR7 | |
| SCHEMBL19924270 | 0.83 | TLR8 (0.72) | KCNH2TLR8TLR7 | |
| SCHEMBL30076157 | 0.83 | TLR8 (0.72) | KCNH2TLR8TLR7 | |
| SCHEMBL19935525 | 0.77 | KCNH2 (0.56) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19924219 | 0.76 | KCNH2 (0.55) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19924220 | 0.76 | KCNH2 (0.55) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL30076138 | 0.76 | KCNH2 (0.55) | KCNH2TLR8TLR7CYP2D6DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124487-B2 | Toll like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124487-B2 | Toll like receptor modulator compounds | TLR8, TLR3, TLR6 | KCNH2 4399/4885TLR8 1/4885TLR7 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.