Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14090164 | 0.92 | HTR2A (0.33) | HTR2AHTR2CHTR2BVHLELOC | |
| SCHEMBL19657863 | 0.88 | AURKA (0.34) | — | |
| SCHEMBL17476448 | 0.88 | AURKA (0.34) | — | |
| SCHEMBL17489316 | 0.84 | POLB (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL19035897 | 0.83 | KDM4E (0.31) | — | |
| SCHEMBL18973168 | 0.83 | KDM4E (0.31) | — | |
| SCHEMBL31151912 | 0.83 | ALPL (0.33) | EGFRACHEHTR2AHTR2CHTR2B | |
| SCHEMBL31151995 | 0.83 | ALPL (0.33) | EGFRACHEHTR2AHTR2CHTR2B | |
| SCHEMBL29778228 | 0.82 | PDE3B (0.38) | HTR2AHTR2CHTR2BVHLELOC | |
| SCHEMBL20169652 | 0.82 | PDE4B (0.39) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882349-A1 | (ANTI-CDH6 ANTIBODY)-(PYRROLOBENZODIAZEPINE DERIVATIVE) CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2021-09-22 | — | — | EP | disclosed |