Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 6/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31151912 | 1.00 | ALPL (0.33) | ALPLACHEHTR2BHTR2AHTR2C | |
| SCHEMBL31151970 | 0.86 | ACHE (0.37) | ALPLACHEHTR2BHTR2AHTR2C | |
| SCHEMBL31151942 | 0.86 | ACHE (0.37) | ALPLACHEHTR2BHTR2AHTR2C | |
| SCHEMBL31151978 | 0.86 | ACHE (0.37) | ALPLACHEHTR2BHTR2AHTR2C | |
| SCHEMBL23837196 | 0.83 | EGFR (0.35) | ACHEHTR2BHTR2AHTR2CEGFR | |
| SCHEMBL31152007 | 0.82 | PDE4B (0.42) | KMT2A | |
| SCHEMBL31151953 | 0.82 | PDE4B (0.42) | KMT2A | |
| SCHEMBL3893507 | 0.80 | ACHE (0.38) | ALPLACHEHTR2BHTR2AHTR2C | |
| SCHEMBL11088844 | 0.80 | ACHE (0.38) | ALPLACHEHTR2BHTR2AHTR2C | |
| SCHEMBL31151905 | 0.79 | ACHE (0.37) | ALPLACHEHTR2BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024235121-A1 | FUSED RING COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-11-21 | — | — | WO | disclosed |